Taurohyodeoxycholic acid sodium salt hydrate

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1 Gram	Negotiable

1 Gram

Negotiable

Min.Order :1 Gram
Purity: 99%
Payment Terms : T/T,,MoneyGram,Other

Keywords

Taurohyodeoxycholic acid sodium salt hydrate 38411-85-7 99%

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Application:intermediate
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ProductionCapacity:1|Kilogram|Day
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Taurohyodeoxycholic acid sodium salt hydrate Basic information
Product Name:   Taurohyodeoxycholic acid sodium salt hydrate
Synonyms:   Taurohyodeoxycholic acid sodium salt hydrate;Taurohyodeoxycholic acid hydrate sodium salt;Sodium taurohyodeoxycholate hydrate,Taurohyodeoxycholic acid sodium salt hydrate
CAS:   38411-85-7
MF:   C26H46NNaO6S
MW:   523.7
Mol File:   38411-85-7.mol

Details:

Description   Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; ) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.
Uses   Sodium taurohyodeoxycholate hydrate has been used in a study to assess dose-response data for cytotoxicity, regenerative cell proliferation and secondary oxidative DNA damage in rat livers treated with furan. It has also been used in a study to investigate the use of an immobilized artificial membrane HPLC column to predict bile salt-membrane interactions.
General Description   Sodium taurohyodeoxycholate hydrate is a taurine-amidated bile salt, which can be used as an anionic detergent.

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