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CAS 24939-03-5 Polyinosinic Acid-Polycytidylic Acid, Poly I: C Polyinosinic-polycytidylic acid sodium salt
Introduction:
Polyinosinic:polycytidylic acid (usually abbreviated poly I:C or poly(I:C)) is an immunostimulant. It is used in the form of its sodium salt to simulate viral infections.
Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed at the endosomal membrane of B-cells, macrophages and dendritic cells. Poly I:C is structurally similar to double-stranded RNA, which is present in some viruses and is a "natural" stimulant of TLR3. Thus, Poly I:C can be considered a synthetic analog of double-stranded RNA and is a common tool for scientific research on the immune system.
Product name | Polyinosinic acid-polycytidylic acid |
CAS No. | 24939-03-5 |
Molecular formula | C19H27N7O16P2 |
Molecular weight | 671.402502 |
Purity | 99% |
Appearance | White or almost white powder |
Package | Aluminum Bag;Drums |
Shelf life | 2 years |
1. A double-stranded homopolymer that can be used as a model RNA to study cell signaling at the level of TLR3-recognized double-stranded RNA. It is also a major effector of the immune response to viral pathogens.
2. Paired with polyinosinic acid to form polyinosin for the treatment of viral hepatitis, herpes zoster, herpes simplex keratitis, herpetic stomatitis, epidemic hemorrhagic fever, etc.
3. It has the function of immune adjuvant, can stimulate the reticuloendothelial system, enhance the phagocytic function of phagocytes, enhance the formation of antibodies, stimulate allograft reactions and delayed allergic reactions. It has broad-spectrum antiviral and antitumor effects. Mainly used in clinical practice: prevention or treatment of viral infection, treatment of herpes zoster, herpetic keratitis, viral hepatitis. Adjuvant therapy of tumors. The main adverse reactions are transient low-grade fever, and individual cases have high fever above 38°C, which mostly subsides within 1-2 days. If the fever does not subside within 2 days, the drug should be discontinued immediately. Fatigue, dry mouth, dizziness, nausea, etc. are still seen.
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Q3.In the third quarter.What is your minimum order quantity
A3.Our minimum order quantity is 1 gram.
Q4.Fourth quarter.Can you provide free test samples
A4.Yes, we can provide 10g free samples for consumer test.
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A5.Delivery takes 2-3 days, depending on the destination.
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Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.
Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.
An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.
1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.
2.We can provide you with ten thousands of products of different levels.
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Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.
The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.
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