Pharmaceutical Powder Lower Price Best Supply Captopril CAS 62571-86-2

Superiority:

English name: Captopril

CAS number: 62571-86-2

Molecular formula: C9H15NO3S

Molecular weight: 217.29

EINECS Number: 263-607-1

Melting point: 104-108°C(lit.)

Specific rotation: -129.5º(c=1, EtOH)

Boiling point: 427.0±40.0°C (Predicted)

Density: 1.2447 (rough estimate)

Refractive index: -127.5°(C=1.7, EtOH)

Storage condition: room temp

Solubility: H2O: 0.1g/mL, very slightly hazy, colorless

Acidity coefficient:(pKa)3.7,9.8(at25℃)

Form:Crystalline Powder

Color: white to off-white

Water solubility:soluble

Merck: 14,177

White or off-white crystalline powder, with a special odor similar to garlic, and a salty taste. Soluble in methanol, ethanol, acetone, dichloromethane or chloroform, soluble in water, insoluble in ether or hexane. There are two crystal forms, which are isomorphous crystals with a melting point of 106°C (stable type) and a melting point of 84-86°C (unstable type); or a melting point of 87-88°C, and then solidified, the second melting point is 104-105°C. [α]D20-126°～-132° (20mg of this product dissolved in 1ml of ethanol). pKl3.7, Pk29.8. Acute toxicity LD50 mice (mg/kg): 1040 intravenously, 6000 orally.

1. Angiotensin-converting enzyme inhibitor, which can significantly reduce blood pressure and reduce cardiac load. Used for different types of high blood pressure, also effective for heart failure. It is compounded with the diuretic hydrochlorothiazide, and its trade names are Capozide and Acezide, which were launched in 1984.

2. Captopril, as an antihypertensive drug, has obvious antihypertensive effect on various types of hypertension, and can improve the cardiac function of patients with congestive heart failure. The LD50 of mice injected intravenously was 1040 mg/kg, and the LD50 of oral administration was 6000 mg/kg.

3. Captopril is used in the treatment of hypertension and heart failure. Captopril is a synthetic non-peptide angiotensin-converting enzyme inhibitor, which mainly acts on the renin-angiotensin-aldosterone system (RAA system). Inhibits the angiotensin-converting enzyme (ACE) of the RAA system, prevents the conversion of angiotensin I or angiotensin II, and can inhibit the secretion of aldosterone and reduce water and sodium retention. It is used for hypertension, and also for heart failure patients who are ineffective to diuretics and digitalis.

4.Captopril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.

Q1.Are you a manufacturer or a trading company
A1.Our company is a leading manufacturer specializing in trade and the development, production and marketing of pharmaceutical intermediates and apis for more than 10 years.
Q2.What about the quality of your products
A2.We value quality as life.We strictly control the quality of each process, established a perfect quality control system.
Q3.In the third quarter.What is your minimum order quantity
A3.Our minimum order quantity is 1 gram.
Q4.Fourth quarter.Can you provide free test samples
A4.Yes, we can provide 10g free samples for consumer test.
Q5.What is your delivery time
A5.Delivery takes 2-3 days, depending on the destination.
Q6.What about the mode of transportation
A6.For urgent and light orders, UPS, FedEx, DHL, EMS can be used;For heavier goods, we provide the method of air or sea transportation to consumers.
Q7.So far.How about the terms of payment
A7.We accept T/T,  Paypal, , money gram, etc.