2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid Endurobol GSK-516
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Quick Detail:
Product Name:Cardarine,GW501516
CAS: 317318-70-0
MF.: c21h18f3no3s2
MW.: 453.5
MW: 330.47
Purity: 98.0%--102.0%. usp32
Appearance: white crystalline powder;
Application: Bodybuilding Muscle Growth
DeliveryTime: within 3 days
Usage: Pharmaceutical material, Steroid hormone, Anabolin. As a male hormone and anabolic hormones.
Description:
1. GW-501516, better known as cardarine, is a unique medication officially classified as a ppar receptor agonist (ppar-ra). research for this medication began in 1992 in a conjoined effort between glaxosmithkline (gsk) and ligand pharmaceuticals.
2. Research into this product was set forth in an effort to provide treatment for various cardiovascular diseases, as well as diabetes, obesity and other conditions.
3. It was soon discovered that the ppar-ra was highly effective at enhancing endurance, but it was also shown to carry a high potential cost. it was discovered that cardarine increased the chances of cancer significantly, and as a result, gsk dropped all further research.
4. However, the studies that produced cancerous results used doses of cardarine that were 500 to even 1000 times the amount that a human being would take. if cancer is a risk with standard dosing is unknown.
5. Cardarine (gw-501516) binds to the ppar receptor, specifically a group of nuclear receptors (sensors that detect thyroid and steroidal hormones in the body) that initiates the pgc-1a enzyme.
6. This action leads to gene expression, specifically genes that revolve around energy expenditure.
studies involving gw-501516 have shown to increase the metabolism of fatty acids in rats.
7. It was also shown in the same studies to reduce the odds of obesity despite poor eating habits as well as prevent type-2 diabetes.
8. Cardarine was also shown to increase hdl (good cholesterol) and decrease ldl (bad cholesterol) in a study using monkeys. the effects seemed to hold true with or without exercise
Gw501516 usage:
It had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease. gw501516 could be used by athletes as an ergogenic performance enhancing drug.
How gw501516 works
Endurobol is a selective agonist (activator) of the pparδ receptor. it displays high affinity (ki = 1 nm) and potency (ec50 = 1 nm) for pparδ with > 1000 fold selectivity over pparα and pparγ.
It activates amp-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and gw 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. it has been proposed as a potential treatment for obesity and related conditions, especially when used in conjunction with a synergistic compound aicar, as the combination has been shown to significantly increase exercise endurance in human
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Delivery time is usually 5-10 days by express delivery
The mode of transportation
Express delivery (EMS, DHL, TNT, FedEX, HKDHL; EUB) bulk airlift door to door.
Delivery time most countries can arrive in 3 to 10 days
Often ask questions
Q1: May I take some samples
A: Yes, we can provide free samples, but the freight will be paid by our customers.
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A: The proforma invoice will be sent first after the order is confirmed with our bank information. Payment via T/T, , or Paypal.
Q3: How to confirm product quality before placing an order
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Q4: What's your minimum order quantity
A: Our minimum order quantity is 1 kg. But we usually accept a smaller quantity, such as 100G, on the condition that the sample fee is 100%.
Q5: What about the lead time
A: Delivery lead time: about 3-5 days after payment confirmation. (excluding Chinese holidays)
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