GMP factory Supply High Purity High Purity CAS 220620-09-7 Tigecycline for Antibiotic

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Tigecycline, A glycylcycline antibiotic, used to treat infection by drug resistant bacteria such as
Staphylococcus aureus (Staph aureus) and Acinetobacter baumannii.

Tigecycline is used to treat different kinds of bacterial infections, including complicated skin
and structure infections, complicated intra-abdominal infections and community-acquired
bacterial pneumonia. The spectrum of activity of tigecycline is discussed below.

  Tigecycline can treat complicated skin and structure infections caused by; Escherichia
coli, vancomycin-susceptible Enterococcus faecalis, methicillin-resistant Staphylococcus
aureus (MRSA), Streptococcus agalactiae, Streptococcus anginosus grp., Streptococcus
pyogenes, Enterobacter cloacae, Klebsiella pneumoniae, and Bacteroides fragilis.

  Tigecycline is indicated for treatment of complicated intra-abdominal infections caused
by; Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Klebsiella oxytoca,
Klebsiella pneumoniae, vancomycin-susceptible Enterococcus faecalis, methicillin-resistant
Staphylococcus aureus (MRSA), Streptococcus anginosus grp., Bacteroides fragilis,
Bacteroides thetaiotaomicron, Bacteroides uniformis, Bacteroides vulgatus, Clostridium
perfringens, and Peptostreptococcus micros.

  Tigecycline may be used for treatment of community-acquired bacterial pneumonia caused
by; penicillin susceptible Streptococcus pneumoniae, Haemophilus influenzae that does not
produce Beta-lactamase and Legionella pneumophila.

1.A broad spectrum glycylcycline antibiotic
2.Uses A glycylcycline antibiotic, used to treat infection by drug resistant bacteria such as Staphylococcus aureus (Staph aureus) and Acinetobacter baumannii.

English name: Tigecycline

CAS number: 220620-09-7

Molecular formula: C29H39N5O8

Molecular weight: 585.65

EINECS Number: 685-736-6

Melting point: 164-166°C

Boiling point: 890.9±65.0°C (Predicted)

Density: 1.45±0.1g/cm3(Predicted)

Storage conditions: Keep in dark place, Inert atmosphere, Store in freezer, under-20°C

Solubility:Soluble in DMSO(up to at least 25mg/ml).

Form:Orange powder

Acidity coefficient: (pKa) 4.50 ± 1.00 (Predicted)

Color:Orange

Merck: 14,9432

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Tigecycline is a broad-spectrum glycyltetracycline antibacterial drug, widely covering G+ cocci, G-bacilli, MRSA, ESBLS-positive Enterobacter, Stenotrophomonas maltophilia and multidrug-resistant Baumannii Bacillus.

Tigecycline is used to treat infections with resistant bacteria such as Staph aureus and Acinetobacter baumannii.

Tigecycline can be used as an option after failure of first-line drug therapy for multidrug-resistant bacteria, and it is also a new treatment option for patients who are allergic to penicillin or who cannot tolerate other drugs. For the treatment of patients 18 years of age and older with complex skin and skin structure infections or complex intra-abdominal infections, including complex appendicitis, burn infections, intra-abdominal abscesses, deep soft tissue infections, and ulcer infections.