99% Raw Material Fa...

99% Raw Material Factory Supply API Tolvaptan CAS 150683-30-0
99% Raw Material Factory Supply API Tolvaptan CAS 150683-30-0
99% Raw Material Factory Supply API Tolvaptan CAS 150683-30-0
99% Raw Material Factory Supply API Tolvaptan CAS 150683-30-0
99% Raw Material Factory Supply API Tolvaptan CAS 150683-30-0

99% Raw Material Factory Supply API Tolvaptan CAS 150683-30-0

Min.Order / FOB Price:Get Latest Price

1 Gram

FOB Price:USD 0.0200 -0.0300

  • Min.Order :1 Gram
  • Purity: 99%+
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Tolvaptan N-{4-[(5RS)-7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl]-3-methylphenyl}-2-methylbenzamide Lower Price Tolvaptan

Quick Details

  • Appearance:White powder
  • Application:Tolvaptan is also the only triptan that can be used for hyponatremia in cirrhosis. Several studies have confirmed that vasopressin receptors V2 and V3 are overexpressed in pituitary and ectopic adreno
  • PackAge:bag or barrel or drum
  • ProductionCapacity:6000|Metric Ton|Day
  • Storage:Store at room temperature
  • Transportation:by express or air or sea

Superiority:

Name Tolvaptan 
Other names N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide
Tolvaptan
N-[4-[(5R)-7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide
N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-Methylphenyl)-2-MethylbenzaMide
OPC 41061
SaMsca
Tolvaptan Tablets
Keywords Inhibitors
Samsca
APIs
Aromatics
Tolvaptan
Other APIs
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
Isotope Labelled Compounds
CAS NO. 150683-30-0
Molecular Formula C26H25ClN2O3
Molecular Weight 448.94
Chemical and Physical Properties
Appearance whtie crystalline powder
Solubility DMSO: ≥15mg/mL
Quality standard  Purity 99%
Application
Drug Indication/Application/Use Tolvaptan(trade names Samsca and Jinarc) is an oral selective vasopressin antagonist developed by Otsuka for the treatment of hyponatremia
Formulations/Preparations SIADH
Handling and Storage
Safety and Hazards Hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required. 
Handling and Storage Sealed in dry,Room Temperature
Sample package Aluminium foil bag,aluminium tin
Commercial package 1kg/Tin,5kg/Tin,25kg/Tin
UN Code Not classified
HS Code 2933990090
Shipping group Shipment at ambient temperature for no controlled and  no dangerous goods
Sales restriction No
Origin China
Technnical support 
STD Data sheet Yes
MSDS Yes
COA Yes
Transport certificate Yes

Related Cosmetic Ingredients

Torasemide
upadacitinib
Valsartan
Supply ability

Tolvaptan was developed by Japan's Otsuka Corporation and was approved by the US FDA in 2009 for the treatment of patients with heart failure. The trade name of tolvaptan tablets is Sumica, and the difficulty of its synthetic route is mainly reflected in the construction of the benzo seven-membered ring. The treatment of heart failure is a research hotspot, and the development of new diuretics is one of its strategic goals. Therefore, antagonizing arginine vasopressin is an effective method to prevent the development of heart failure.

Tolvaptan is also the only triptan that can be used for hyponatremia in cirrhosis. Several studies have confirmed that vasopressin receptors V2 and V3 are overexpressed in pituitary and ectopic adrenocorticotropic hormone (ACTH) tumors, and selective V2 and V3 receptor antagonists may have therapeutic effects against ACTH-secreting tumors , but this needs to be confirmed by further research.

Details:

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together.  Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.


1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions. 
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

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