Pharmaceutical Intermediate API Ketoconazole Powder CAS 65277-42-1 99% Ketoconazole Organic Intermediate Medicine Material Food Additive in Stock

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 What is Ketoconazole 

Ketoconazole is a broad-spectrum antifungal imidazole, which interferes with the activity of fungal cytochrome P-450 with high selectivity, thereby inhibiting the biosynthesis of ergosterol in fungal cell membranes.

Function of Ketoconazole 

It is effective in the treatment of both shallow and deep fungal infections, and can inhibit the growth of fungi and the transformation from spores to mycelium to prevent further infections. It has antifungal effects on Candida, Fonsecaea, Coccidioides, Histoplasma, Sporothrix and Trichophyton.

Application of Ketoconazole 

Ketoconazole is also sometimes prescribed by veterinarians for use on pets, often as unflavored tablets that may need to be cut to smaller size for correct dosage.

1. Imidazole antifungal drugs.

2. It is an antifungal drug for the treatment of athlete's foot and excessive dandruff

3. A broad-spectrum antifungal drug that is a CYP3A4 inhibitor

Ketoconazole is an imidazole broad-spectrum antifungal drug, which is sold under the trade names of Jindakning, Miconing and Kening. It inhibits the fungal cell membrane by highly selectively interfering with the activity of fungal cytochrome P-450. Biosynthesis of ergosterol. It is effective for both superficial and deep fungal infections, not only inhibiting the growth of fungi, but also inhibiting the transformation of spores into mycelium, preventing further infection. Low concentration bacteriostatic, high concentration bactericidal. It has antibacterial effect on Candida, Chromophytes, Coccidioides, Histoplasma, Sporothrix and Trichophyton. It is clinically suitable for the treatment of tinea pedis, tinea pedis, tinea pedis, tinea corporis, tinea cruris, oral thrush, tinea versicolor and skin candidiasis. Ketoconazole lotion is used as an external drug for the skin. It is mainly used in clinical treatment and prevention of various infections caused by Malassezia, such as tinea versicolor, seborrheic dermatitis and pityriasis scalp (dandruff), and can quickly relieve the symptoms caused by Scaling and itching due to seborrheic dermatitis and pityriasis scalp.

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Ketoconazole is suitable for the treatment of the following systemic fungal infections:

1. Candidiasis, chronic skin and mucous membrane candidiasis, oral candidiasis, urinary tract candidiasis, chronic and recurrent vaginal candidiasis for which local treatment is ineffective.

2. Dermatitis blastomycosis.

3. Coccidioidomycosis.

4. Histoplasmosis.

5. Color fungal disease.

6. Paracoccidioidomycosis. Dermatomycosis, tinea versicolor and tinea versicolor caused by dermatophytes and yeast, when topical treatment or oral griseofulvin is ineffective, or severe stubborn dermatophyte infection that is difficult to receive griseofulvin treatment, this product can be used treat.