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Product Description

Description

Cas No.: 50-14-6                                    EINECS No.: 200-014-9

Molecular Formula: C28H44O                Molecular Weight: 396.65

Solubility: Freely soluble in alcohol 

Should be a white to light yellow powder, give out no smell no taste; be easy to lose activity in air or light.
 

Function:

Vitamin D2 in promoting intestinal brush border calcium absorption and renal tubular reabsorption of phosphorus, increasing the concentration of serum calcium, serum phosphorus, in collaboration with parathyroid hormone (PTH), calcitonin (CT), old bones to release calcium phosphate, normal maintenance and regulation of plasma calcium and phosphorus concentration. Vitamin D2 is promoting the formation of new bone calcium deposition in parts, the citrate salt deposition in bone, bone calcification and bone cell function and bone-like tissue to mature.

Application: 

1.For the prevention and treatment of vitamin d deficiency. Such as vegans, parenteral nutrition patients, pancreatic dysfunction with malabsorption syndrome, liver and gallbladder diseases (liver damage, liver cirrhosis and obstructive jaundice), intestinal disease (fatty diarrhea, diarrhea in Crohn's, chronic), gastric resection.

2.Used in chronic hypocalcemia, hypophosphatemia, and rickets and osteomalacia associated with chronic renal insufficiency syndrome, familial hypophosphatemia and hypoparathyroidism (false hypoparathyroidism, idiopathic or after) treatment.

3.for the treatment of acute and chronic and potential contraction of the hands and feet and after surgery of idiopathic with contraction of the hands and feet.

English name: Vitamin D2

CAS Number: 50-14-6

Molecular formula: C28H44O

Molecular weight: 396.65

EINECS No.: 200-014-9

Melting point: 114-118°C(lit.)

Specific rotation: 82º(c=3,inacetone25ºC)

Boiling point: 460.3°C (rough estimate)

Density: 0.9784 (rough estimate)

Vapor pressure: 7xl0-7Pa(20°C),est.)

Refractive index: 1.5100 (estimate)

Flash point: 14°C

Storage conditions: -20°C

Solubility: H2O: 200mg/mL, cleartohazy

Acidity coefficient: (pKa) 14.74±0.20 (Predicted)

Form: powder

Color: white to yellowish

Optical activity: (opticalactivity)[α]20/D+105±2°, c=4%inethanol

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1. Vitamin D2 is a steroid derivative and is an active substance related to calcium and phosphorus metabolism. It plays an important role in the prevention and treatment of rickets in children and osteoporosis in the elderly. At present, there are 96 kinds of pharmaceutical preparations with vitamin D2 as the main component; vitamin D2 is also An indispensable and important additive in feed, it can significantly improve the egg production rate and lean meat rate of livestock; vitamin D2 is also a synthetic raw material for drugs such as doxocalcidol, calcitriol, calcipotriol and paricalcitol , so it is a very important drug and fine chemical product.

2. Biochemical research; clinical drugs are fat-soluble vitamins, which can promote the absorption of calcium and phosphorus in the intestine and help bone calcification. It is clinically used for the prevention and treatment of rickets in children and osteomalacia in adults.

3. Vitamin D2 can maintain the normal metabolism of calcium and phosphorus, and can promote the body's absorption of calcium and phosphorus. When it is lacking, children are prone to rickets.

4. Mainly used for the prevention and treatment of rickets and osteomalacia. It can be converted from sterol by ultraviolet light irradiation. 5. Mainly used for the prevention and treatment of rickets, osteomalacia, infant tetany, etc.