Pharmaceutical intermediates Chemical Powder Anti-Hyperlipidemia Nice Price CAS 79902-63-9 99% Simvastatin

Pharmaceutical intermediates Chemical Powder Anti-Hyperlipidemia Nice Price CAS 79902-63-9 99% Simvastatin

Min.Order / FOB Price:Get Latest Price

1 Gram	FOB Price:USD 0.0200 -0.0300

1 Gram

FOB Price:USD 0.0200 -0.0300

Min.Order :1 Gram
Purity: 99%+
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Simvastatin Lower Price Simvastatin Chemical Powder

Quick Details

Appearance:White to off-white powder
Application:1. HMG-CoA reductase inhibitor can reduce the concentration of serum total cholesterol and inhibit cholesterol synthesis. It is used for the treatment of primary hypercholesterolemia in which other tr
PackAge:bag or barrel or drum
ProductionCapacity:6000|Kilogram|Day
Storage:Store at room temperature
Transportation:by express or air or sea

Superiority:

1, We offer competitive factory price for both wholesalers and retailers.
2, Fast reply for inquiries.
3, Stable Quality, high purity.
4, We offer EXW/FOB/CFR/DAP/DDP trade terms for your option.
5, Fast Delivery for shipment and Safe for destination custom clearance.
6, Free samples.
7, Free custom clearance with freight prepaid, delivery door to door.
8, More than 22 years export experience in this field.

Product Name:	Simvastatin
Synonyms:	(1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste;7-beta,8-beta(2s,4s),8a-beta))-alph;[1S-[1α,3α,7β,8β(2S^<>^,4S^<>^),8αβ]-2,2-Dimethylbutanoic acid 1,2,3,7,8,8α-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-y1)ethyl]-1-naphthyl ester;Lodaiès;[(1S,3R,7R,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-oxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoat;Butanoic acid, 2,2-dimethyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro- 4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1-alpha,3-alpha,7- beta,8-beta(2S,4S),8a-beta));[8-[2-(4-Hydroxy-6-oxo-tetrahydropyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]2,2-dimethylbutanoate;2,2-Dimethylbutanoic acid (1S)-1,2,3,7,8,8aα-hexahydro-3β,7α-dimethyl-8α-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]naphthalen-1β-yl ester
CAS:	79902-63-9
MF:	C25H38O5
MW:	418.57
EINECS:	616-751-8

White crystalline powder, odorless. Soluble in ethanol, difficult soluble in ether, practically insoluble in water. Melting point is 135~138 ºC.
Simvastatin is a cholesterol-lowering drug of statin, is a synthetic derivative of Aspergillus terreus fermentation product, is used to control blood cholesterol levels and prevent cardiovascular disease.
Simvastatin belongs to methyl hydroxyl coenzyme A (HMG-COA) reductase inhibitors, inhibits synthesis of endogenous cholesterol, and is the lipid regulator. Has a role in reducing cholesterol (TC) content of serum, liver and aorta in hyperlipidemia rabbits reducing levels of very low density lipoprotein cholesterol (VLDL-C) and low-density lipoprotein cholesterol (LDL-C).
1. HMG-CoA reductase inhibitors, can reduce the concentration of serum total cholesterol level, inhibit synthesis of cholesterol. For treatment of primary hypercholesterolemia with cholesterol levels greater than 7.8mmol/L which is invalid or not tolerated in other treatments.
2. Has role in reducing cholesterol, low-density lipoprotein cholesterol and very low density lipoprotein cholesterol.

English name: Simvastatin CAS number: 79902-63-9 Molecular formula: C25H38O5 Molecular weight: 418.57 EINECS Number: 616-751-8 Melting point: 127-132°C(lit.) Specific rotation: D25+292°(c=0.5%inacetonitrile) Boiling point: 564.9±50.0°C (Predicted) Density: 1.11±0.1g/cm3(Predicted) Storage condition: 2-8°C Solubility DMSO: ≥20mg/mL Acidity coefficient: (pKa) 13.49±0.40 (Predicted) Form:solid Color:white Optical activity: (opticalactivity)[α]/D+275±25°, c=1inacetonitrile Merck: 14,8539

Simvastatin is a statin hypolipidemic drug, a synthetic derivative of the fermentation product of Aspergillus terreus, used to control the content of cholesterol in the blood and prevent cardiovascular diseases. Simvastatin is a methylhydroxyglutaryl coenzyme A (HMG-COA) reductase inhibitor, inhibits the synthesis of endogenous cholesterol, and is a blood lipid regulator. It can reduce the content of cholesterol (TC) in serum, liver and aorta of hyperlipidemia rabbits, and reduce the levels of very low density lipoprotein cholesterol (VLDL-C) and low density lipoprotein cholesterol (LDL-C).

1. Hyperlipidemia: (1) For patients with primary hypercholesterolemia, heterozygous familial hypercholesterolemia or mixed hypercholesterolemia, when dietary control and other non-drug treatments are not ideal, the Vastatin may be used to lower elevated total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides. And simvastatin increases high-density lipoprotein cholesterol, thereby reducing the ratios of low-density lipoprotein/high-density lipoprotein and total cholesterol/high-density lipoprotein. (2) For patients with homozygous familial hypercholesterolemia, when dietary control and non-dietary therapy are not ideal, simvastatin can be used to reduce elevated total cholesterol, low-density lipoprotein cholesterol and apolipoprotein B. 2. Coronary heart disease: For patients with coronary heart disease, simvastatin can be used to: (1) reduce the risk of death. (2) Reduce the risk of coronary heart disease death and non-fatal myocardial infarction. (3) Reduce the risk of stroke and transient cerebral ischemia. (4) Reduce the risk of myocardial recanalization surgery (coronary artery bypass grafting and percutaneous balloon coronary angioplasty). (5) Delay the progression of atherosclerosis, including the occurrence of new lesions and total blockage.

White crystalline powder, odorless. It is easily soluble in ethanol, acetone or acetonitrile, difficult to dissolve in ether, and almost insoluble in water. Melting point 135～138 ℃.

1. HMG-CoA reductase inhibitor can reduce the concentration of serum total cholesterol and inhibit cholesterol synthesis. It is used for the treatment of primary hypercholesterolemia in which other treatments are ineffective or intolerable and the cholesterol level exceeds 7.8mmol/L. 2. Has the effect of lowering cholesterol, low-density lipoprotein cholesterol and very low-density lipoprotein cholesterol

Details:

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.

1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world

View All

Visit Store

Pharmaceutical inte...