Pharmaceutical Intermediate Sulfamethoxazole Powder CAS 723-46-6 Wholesale Price

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English name: Sulfamethoxazole CAS Number: 723-46-6 Molecular formula: C10H11N3O3S Molecular weight: 253.28 EINECS Number: 211-963-3 Melting point: 166°C Boiling point: 482℃ Density 1.3915(rough estimate) Refractive index: 1.6630 (estimate) Flash Point: >110°(230°F) Storage conditions: Keep in dark place, Inert atmosphere, Room temperature

Sulfonamides have a broad antibacterial spectrum and have certain inhibitory effects on most Gram-positive and negative bacteria, but different sulfonamides have different antibacterial effects. With the wide application of sulfa drugs, drug-resistant strains will also be easily formed, especially Staphylococcus aureus has more opportunities to develop drug resistance. Sulfonamides can be classified into two categories according to their absorption after oral administration. The first category is easily absorbed sulfonamides, which are characterized by fast absorption. Generally, the blood concentration of sulfonamides is 2 to 4 hours after taking the drug (after 5 hours for long-acting drugs). The peak can be reached, and this type of sulfonamides is mainly used for systemic infections. The other type is not easily absorbed or absorbed very little after oral administration, and most of them are excreted through the intestinal tract, mainly used for intestinal infections. Sulfamethoxazole, also known as sulfamethoxazole, is a broad-spectrum antibacterial drug that has a particularly strong effect on Staphylococcus and Escherichia coli, and is used to treat urinary tract infections and avian cholera. Sulfamethoxazole is a systemic medium-acting sulfonamide drug, which can compete with PABA to act on the dihydrofolate synthase in bacteria, preventing the synthesis of bacterial dihydrofolate, thereby inhibiting the growth and reproduction of bacteria. Together with sulfadiazine, sulfisoxazole and trisulfadiazine, three sulfa drugs are currently the best drugs for the treatment of nocardiosis. Half-life of 10 to 12 hours, can be partially acetylated.

White crystalline powder, odorless, slightly bitter taste. Melting point 168 ℃. Very slightly soluble in water, easily soluble in dilute acid, dilute lye or ammonia.

1. As an antibacterial agent, it is particularly effective against Staphylococcus and Escherichia coli. Mainly used for the treatment of fowl cholera and so on. 2. Anti-infective drugs for the prevention of urinary tract infections, respiratory tract infections, intestinal infections, Salmonella infections, acute otitis media in children, and meningitis 3. Sulfonamides, mainly used for the treatment of acute and chronic urinary tract infections, can also be used for the prevention of meningitis and acute otitis media caused by influenza bacillus, etc. 4. This product can inhibit the growth of bacteria, has a particularly strong effect on Staphylococcus and Escherichia coli, and has a good effect on treating urinary tract infections and poultry clutter. 5. Sulfamethoxazole is white crystalline powder; odorless, slightly bitter taste. This product is almost insoluble in water, but easily soluble in dilute hydrochloric acid, sodium hydroxide test solution or ammonia test solution. Melting point The melting point of this product is 168～172℃. 6. This product is white crystalline powder; odorless, slightly bitter taste. This product is almost insoluble in water, but easily soluble in dilute hydrochloric acid, sodium hydroxide test solution or ammonia test solution. Melting point The melting point of this product is 168～172℃. 7. Sulfonamide antibiotics, inhibit the enzyme dihydropteroate synthase (enzyme dihydropteroate synthase), thereby blocking the synthesis of dihydrofolate. Mode of action: Inhibits the synthesis of folic acid in prokaryotes.