Professional Supplier Monomethyl Auristatin E CAS 474645-27-7 for Anti Cancer

Professional Supplier Monomethyl Auristatin E CAS 474645-27-7 for Anti Cancer

Min.Order / FOB Price:Get Latest Price

3000 Kilogram	FOB Price:USD 0.0200 -0.0300

3000 Kilogram

FOB Price:USD 0.0200 -0.0300

Min.Order :3000 Kilogram
Purity: 99%+
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

MonoMethyl auristatin E MMAE VcMMAE

Quick Details

Appearance:White to off-white powder
Application:Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10, which acts as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic c
PackAge:bag or barrel or drum
ProductionCapacity:6000|Kilogram|Day
Storage:Store at room temperature
Transportation:by express or air or sea

Superiority:

English name: MonoMethyl auristatin E

CAS number: 474645-27-7

Molecular formula: C39H67N5O7

Molecular weight: 717.98

Melting point:>90°C(dec.)

Boiling point: 873.5±65.0°C (Predicted)

Density: 1.088±0.06g/cm3(Predicted)

Storage conditions: -20°C Freezer

Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)

Acidity coefficient: (pKa) 13.66±0.20 (Predicted)

Form:Solid

Color: White to Off-White

Monomethyl auristatin E is an anti-mitotic agent that inhibits cell division by blocking the polymerization of tubulin, and has attracted much attention in antibody-drug conjugates (ADCs).

Monomethyl auristatin E, referred to as MMAE, is a synthetic antitumor drug. Due to its toxicity, it cannot be used as a drug by itself but is linked to a monoclonal antibody (MAB). It is a potent antimitotic drug derived from a polypeptide called dolastatin, which is present in the marine shellless mollusk Dolabellaauricularia. These polypeptides have shown potent in vitro and in vivo activity against a variety of lymphomas, leukemias and solid tumors in preclinical studies. These drugs are up to 200 times more potent than vinblastine.

Service:
1. Supply high quality products with a reasonable price.
2. Keep shipment in time, provide complete customers clearance documents as customs request.
3. Provide agile and safe payments.
4. We will responsible for all quality issue.
5. Share marketing informations with customers update price in time.

FAQ:

1. What's your payment terms
T/T, D/P, L/C, O/A
2. What's your delivery time
Usually we will arrange the shipment within 14 days.
3. How about the packing
Usually with 25 kg bag/carton/drum.
4. How about the validity of the products
Usually 2 or 3 years.
5. What documents you provide
Usually, Commerical Invoice, Packing List, Country of Origin, Insurance Policy, Bill of loading, COA , Health certificate.
6. What is loading port
Usually, Qingdao, Tianjin and Shanghai

Details:

Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.

Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.

An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.

1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.

Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.

The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.

[Assay Determination]: 99.0%~101.0% (dries basis)
[Related Substance]:the single impurity≤0.1%, total impurities≤2.0%
[Package and Storage Condition]: 25kg/drum, store and seal away from light