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Vancomycin hydrochloride Vancomycin Hcl Vancomycin hydrochloride from Streptomyces orientalis
English name: Vancomycin hydrochloride CAS Number: 1404-93-9 Molecular formula: C66H76Cl3N9O24 Molecular weight: 1485.71 EINECS Number: 604-193-8 Melting point:>190°C(dec.) Specific rotation: [α]D20-30~-40゜(c=1,H2O) Flash point: 87℃ Storage conditions: 2-8°C Solubility:H2O:50mg/mL,clear,yellow Form: Powder Color: colorless to faint yellowor tan PH value: pH (50g/l, 25℃): 2.5~4.5
Vancomycin hydrochloride is a glycopeptide antibiotic. It is the hydrochloride of vancomycin. It is a white or off-white crystalline powder at room temperature. Alanylalanine blocks the synthesis of high-molecular-weight peptidoglycan that constitutes bacterial cell walls, resulting in cell wall defects and killing bacteria. In addition, it may also alter bacterial cell membrane permeability and selectively inhibit RNA synthesis. Vancomycin hydrochloride is characterized by strong bactericidal effect on Gram-positive bacteria, strong antibacterial activity on Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus pneumoniae, etc.; on anaerobic Streptococcus , Clostridium difficile, Bacillus anthracis, Actinomycetes, Bacillus diphtheriae, Neisseria gonorrhoeae, Streptococcus viridans, Streptococcus bovis, Streptococcus faecalis, etc. also have certain antibacterial effects. It is ineffective against most gram-negative bacteria, mycobacteria, rickettsia, chlamydia or fungi. It is clinically suitable for the treatment of infections caused by methicillin-resistant Staphylococcus aureus and other bacteria: sepsis, infective endocarditis, osteomyelitis, arthritis, burns, surgical trauma and other superficial secondary infections, pneumonia , Lung abscess, empyema, peritonitis, meningitis, pseudomembranous colitis, skin and soft tissue infections, etc. The drug of choice for the treatment of enterococcal endocarditis and Corynebacterium (diphtheroid-like) endocarditis in penicillin-allergic patients.
1. Narrow antibacterial spectrum, mainly effective against Gram-positive bacteria
2. It is a narrow-spectrum antibiotic and is only effective against gram-positive bacteria, such as hemolytic streptococcus, pneumococcus, gonococcus and enterococcus, which are all sensitive, especially sensitive to drug-resistant Staphylococcus aureus. Its mechanism of action is to inhibit the synthesis of bacterial cell wall, it is mainly combined with bacterial cell wall, and some amino acids cannot enter the glycopeptide of the cell wall.
Wuhan Kanal Technology Co., Ltd. founded in 2010,it is a large manufacturer of fine Pharmaceutical& Chemical & Cosmetic materials that integrates R&D, production and sales together. Our Kanal company is established under the support of the Wuhan city government, so Kanal has large advantages in enterprise credit, finance security, product quality control, and cargo export.Kanal locates in the national new materials industry park of Wuhan city and is awarded the title of high-tech corporation.
Wuhan Kanal has its own R&D and development laboratory. We Kanal set up a R&D team with rich experience and strong technical strength, most of the practitioners have more than ten years' experience and technology in organic synthesis development. It owns almost 15 acre and more than 280 workers.
An ISO 9001 & GMP qualified company, we are mainly specialized in producing high quality but low price Pharmaceutical intermediates, APIs and other fine chemicals & cosmetics products which related to human and animals medicines as well as additives in gas &oil field, almost half of the goods are for exporting. What's more, we provide the OEM (customize) manufactures, if you can't find materials from the world, then tell us, we will research and produce in our high-tech equipmented laboratory. We are dedicated to satisfying our customers with our products and services.
1. We has 11 years' exporting experience in active pharmaceutical ingredient products.
Our professional and thoughtful after-sales service eliminates your worries.
2.We can provide you with ten thousands of products of different levels.
3. We offer convenient one-station purchasing service.
(1)Any inquiries will be replied within 12 hours.
(2)Dedication to quality, supply & service.
(3)Strictly on selecting raw materials.
(4)Reasonable & competitive price, fast lead time.
Our company is based on the optical valley biological city,making full use of the park policy advantages, focusing on the research and development of biological medicine.
The pharmaceutical intermediates are mainly applied to anti-cancer, anti-depression, cardiovascular, diabetes and other new medicine. The chemical intermediates mainly refer to heterocyclics and OLED intermediates.Our factory produce new fine chemical materials which are mainly used in water treatment, bactericidal and anti-corrosion, dyes, electronic materials and other industry fields.
Wuhan Kanal has export & import license, and hazard chemical sales license. The products are exported to America, Brazil, South Korea, Japan, Taiwan, Malaysia, Thailand, Indonesia, Europe union and other countries or regions.
Under rich experiences and excellent international reputation, the company becomes a quite influential enterprise in China's API field. Wuhan Kanal sincerely look forward to establishing long good cooperation with our customers from all over the world.
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