High Quality Raw Ma...

High Quality Raw Material Decitabine Powder CAS 2353-33-5 Decitabine
High Quality Raw Material Decitabine Powder CAS 2353-33-5 Decitabine

High Quality Raw Material Decitabine Powder CAS 2353-33-5 Decitabine

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : D/A,D/P,T/T,

Keywords

Decitabine 2353-33-5 high purity Decitabine

Quick Details

  • Appearance:White powder
  • Application:Decitabine (NSC 127716) is a DNA methyltransferase inhibitor commonly used to treat myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML).
  • PackAge:Independent sealed packaging
  • ProductionCapacity:10000|Kilogram|Month
  • Storage:seal preservation
  • Transportation:by sea or by air

Superiority:

1.Fast and safety delivery by well-reputed shipping line;
2.we have our own chemical laboratory and factory
3.Reasonable price, excellent quality and attentive service.
4.prompt reply.we can reply your inquiry within 12 hours.
5.sample free(depends on product,we just collect courier fee, or give us your express account NO.)
6.Rich experience in loading a great amount of containers
7.Sperior quality and good package

8.The product and package can be customed according cusomter's requirement.

Details:

High Quality Raw Material Decitabine powder CAS 2353-33-5 Decitabine
 

Product Name High Quality Raw Material Decitabine powder CAS 2353-33-5 Decitabine
Appearance white powder
Molecular formula C8h12n4o4
Molecular Weight 228.20
Keywords Raw Material Decitabine;Decitabine powder;Decitabine
Shelf Life 24 months when properly stored
Storage Keep in a cool, dry, dark location

 

  What is Decitabine

Decitabine (trade name Dacogen), or 5-aza-2'-deoxycytidine, is adrug for the treatment of myelodysplastic syndromes, a class of conditions where certain blood cells are dysfunctional, and for acute myeloid leukemia (AML).Chemically, it is a cytidine analog.

Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.

It functions in a similar manner to azacitidine, although decitabine can only be incorporated into DNA strands while azacitidine can be incorporated into both DNA and RNA chains. 


Function of Decitabine

High Quality Raw Material Decitabine powder CAS 2353-33-5 Decitabine

Application of Decitabine

Decitabine is indicated for the treatment of myelodysplastic syndromes (MDS) including previously treated and untreated, de novo and secondary MDS of all French-American-British subtypes (refractory anemia,refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, and chronic myelomonocytic leukemia) and Intermediate-1, Intermediate-2, and High-Risk International Prognostic Scoring System groups. In patients with renal insufficiency, Batty and colleagues reported the first case series on the feasibility of therapy with hypomethylating agents in patients with renal insufficiency.

 

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