Estrogen Receptor (ER) PROTAC Degrader Arv471

Min.Order / FOB Price:Get Latest Price

100 Gram	Negotiable

100 Gram

Negotiable

Min.Order :100 Gram
Purity: 99.60%
Payment Terms : L/C,D/P,T/T,

Keywords

Estrogen Receptor (ER) PROTAC Degrader 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-ph enyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-, (3S)- Arv471

Quick Details

Appearance:White to off-white (Solid)
Application:ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
PackAge:based on your requests.
ProductionCapacity:500|Kilogram|Year
Storage: -20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Transportation:Room temperature in continental US; may vary elsewhere.

Superiority:

Our Strength

1) Quick Response Within 12 hours;

2) Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, Accept any third party agency inspection and analysis before shipment from your side.

3) OEM/ODM is available; we have professional engineer to design the fomulation with you together.

4) Mature products with factory and technical support. Reasonable & Competitive Price;

5) Fast Delivery: Samples from stock; bulk products within 7 days;

6) Professional SOP for exporting chemical and pharmaceitical intermediates

7) UPS,Fedex,TNT,EMS,EUB are available by air for small sample quality order to save your cost. frree samples are confirmed before mass production order.

8) Payment: T/T, L/C, paypal, .

9) A good troubleshooter/very positive attitude for after service

Our service:

1. Certificate Of Analysis (COA)

2. Material Safety Data Sheet (MSDS)

3. Route of synthesis (ROS)

4. Method of Aanlysis (MOA)

5. Nuclear Magnetic Resonance (NMR)

6. Inquiry: Tell us the chemical name, CAS NO and Quanity to move forward to the business discussion.

Details:

Estrogen Receptor (ER) PROTAC Degrader Arv471

About US	Xinyang Longye Chemical Products Co., Ltd. is a high-tech enterprise integrating science, industry and trade, and holds a certain authoritative position in the brightener chemical industry. It mainly develops and sells fluorescent brighteners, pharmaceutical intermediates, electronic chemical products and other fine chemical products, which are widely used in medicine, electronics, environmental protection, plastics, textiles, daily chemicals and other fields. After hundreds of users use, it has received praise and trust from customers.
Description	ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
Applicaiton	Usage: Estrogen Receptor/ERR; PROTACs Vepdegestrant (ARV-471) is an oral estrogen receptor PROTAC protein degrader for breast cancer. Vepdegestrant is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex. Vepdegestrant leads to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. Vepdegestrant robustly degrades ER in ER-positive breast cancer cell lines with a half-maximal degradation concentration (DC₅₀) of ~2 nM
Packing	1. Free samples are available 2. small quanity will be sent by courior or air, mass production will ship by sea 3. by carton or based on your requirements.
Chemical Experience	RD Engineer and sales engineer have more than 20 years experience in chemicals and pharmaceitical intermediates
Market	China, India