Dehydroepiandrosterone acetate 853-23-6 99%
Dehydroepiandrosterone acetate Basic information
Product Name: Dehydroepiandrosterone acetate
Synonyms: 3B-ACETOXY-5-ANDROSTEN-17-ONE;3BETA-ACETOXY-5-ANDROSTEN-17-ONE;3BETA-ACETOXY-5-ANDROSTEN-17-ONE ACETATE;3B-HYDROXYANDROST-5-EN-17-ONEACETATE;3-(ACETYLOXY)ANDROST-5-ENE-17-ONE;5-ANDROSTEN-3-BETA-ACETOXY-3-ONE;5-ANDROSTEN-3BETA-OL-17-ONE 3-ACETATE;5-ANDROSTEN-3-BETA-OL-17-ONE ACETATE
CAS: 853-23-6
MF: C21H30O3
MW: 330.47
EINECS: 212-714-1
Product Categories: Intermediates & Fine Chemicals;17-Ketosteroids;Pharmaceutical Intermediates;Biochemistry;Hydroxyketosteroids;Chemistry;Steroids;Metabolites & Impurities;Pharmaceuticals;API;Inhibitors
Mol File: 853-23-6.mol
Dehydroepiandrosterone acetate Chemical Properties
Melting point 168-170 °C(lit.)
Boiling point 407.89°C (rough estimate)
density 1.0998 (rough estimate)
vapor pressure 0Pa at 20℃
refractive index 1.5192 (estimate)
storage temp. Refrigerator
optical activity [α]20/D +2.4°, c = 2 in ethanol
Water Solubility 11.5mg/L(temperature not stated)
InChIKey NCMZQTLCXHGLOK-KJBVPOJVSA-N
LogP 5.1 at 20℃
CAS DataBase Reference 853-23-6
Dehydroepiandrosterone acetate Usage And Synthesis
Chemical Properties Off-White Solid
Uses Menopausal syndrome
Uses A metabolite of Dehydroepiandrosterone. This mammalian pro-hormone promotes brain and immune function
Flammability and Explosibility Notclassified
Biological Activity Dehydroepiandrosterone acetate (DHEA, Androstenolone) is a kind of dehydroepiandrosterone derivatives. DHEA is an endogenous steroid hormone, which is considered to be a natural product/dietary supplement with many proposed benefits to humans.
in vivo Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.
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