Epiandrosterone acetate

Details:

Epiandrosterone acetate Basic information
Product Name:    Epiandrosterone acetate
Synonyms:    3-BETA-HYDROXY-5-ALPHA-ANDROSTAN-17-ONE 3-ACETATE;3-BETA-ACETOXY-5-ALPHA-ANDROSTAN-17-ONE;5-EPIANDROSTER-17-ONE ACETATE;5-ALPHA-ANDROSTAN-3-BETA-OL-17-ONE ACETATE;5ALPHA-ANDROSTAN-3BETA-OL-17-ONE 3-ACETATE;ACETIC ACID (3S,5S,8R,9S,10S,13S,14S)-10,13-DIMETHYL-17-OXO-HEXADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-YL ESTER;ISOANDROSTERONE ACETATE;EPIANDROSTERONE ACETATE
CAS:    1239-31-2
MF:    C21H32O3
MW:    332.48
EINECS:    623-940-9
Product Categories:    Steroids;Pharmaceutical Intermediates
Mol File:    1239-31-2.mol

Uses and methods of synthesis of dehydroepiandrosterone acetate Uses for medicinal use as a norethinone intermediate Use as an intermediate in birth control pills. Production method: Ethanol, hydroxylamine hydrochloride and pyridine were stirred for reflux dissolution, followed by acetic dienolone, continued reflux for 3h, cooled to 5℃, filtered, filter cake washed with ethanol, and then washed with warm water until neutral and dry, acetic dienolone oxime was obtained. Then, the Chemicalbook latter with benzene, pyridine stirred to about 0℃, slowly add the mixture of phosphorus oxychloride and benzene, reaction at 4-7℃ for 3h. Hydrolyzed with hydrochloric acid and kept at 5℃ for 2h. After the benzene layer is washed with water, steam distillation is carried out. After the benzene is evaporated, light yellow solid precipitates out. After filtration, water is washed to neutral and dried at 80℃, hydroepiandrosterone acetate is obtained.