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4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy CAS NO.2226-96-2 EINECS 218-760-9 TMHPO/IN701/ZJ-701/tempol UV-1198
Name | 4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy |
CAS | 2226-96-2 |
EINECS | 218-760-9 |
Molecular Formula | C9H18NO2 |
Molar Mass | 172.24 |
Density | 1.0402 (rough estimate) |
Melting Point | 69-71°C(lit.) |
Boling Point | 302.58°C (rough estimate) |
Flash Point | 146°(295°F) |
Water Solubility | soluble |
Solubility | 1670g/l |
Vapor Presure | 0.025Pa at 20℃ |
Appearance | Crystals or Crystalline Powder |
Color | Orange |
Merck | 14,9141 |
pKa | 5.07[at 20 ℃] |
PH | 8.2 (20g/l, H2O, 20℃) |
Storage Condition | 2-8°C |
Stability | Stable. Incompatible with strong oxidizing agents. |
Refractive Index | 1.4350 (estimate) |
Use | Used as spin labels for the study of biological compounds and polymers; Spin labeling reagents for the identification of antagonist and agonist binding sites for NK1 receptors, it can also be used to detect the production of reactive oxygen species in myocardium by electron spin resonance spectroscopy. TEMPOL can protect cells overexpressing CYP2E1 from the toxic damage of arachidonic acid; used as a fluorine-labeled TEMPO derivative that can be prepared from a derivatized TEMPO propynyl ether and subsequent "click" reaction with fluoroazide; Used as a highly efficient catalyst in the oxidation of alcohols with bleach |
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