Details:

Product  Description：

Product Name:	Rosmarinic acid
CAS:	20283-92-5
MF:	C18H16O8
MW:	360.31
EINECS:	606-487-1
Melting point	171-175 °C (lit.)
alpha	+102～+110°(D/20℃)(c=0.2,C2H5OH)
Boiling point	694.7±55.0 °C(Predicted)
density	1.33
storage temp.	2-8°C
solubility	Soluble in ethanol, DMSO or dimethyl formamide to approximately 25 mg/mL.
form	powder
pka	2.78±0.10(Predicted)
color	white to faintly beige
BRN	2227587

Uses:

1. Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid. It is commonly found in species of the Boraginaceae and the subfamily Nepetoideae of the Lamiaceae. However, it is also found in species of other higher plant families and in some fern and hornwort species. Rosmarinic acid has a number of interesting biological activities, e.g. antiviral, antibacterial, antiinflammatory and antioxidant. The presence of rosmarinic acid in medicinal plants, herbs and spices has beneficial and health promoting effects. In plants, rosmarinic acid is supposed to act as a preformed constitutively accumulated defence compound.[sciencedirect]
2. Rosmarinic acid (RA) is one example of a naturally occurring phenolic compound in plants. RA is especially high in Salvia officinalis (garden sage). As an antioxidant, RA possesses both health benefits, and is useful as a food additive to keep foods fresh.Recently, Bakota et al. successfully prepared an extract of Salvia officinalis at three times the levels from sage leaves alone.[thermofisher]
3. Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells. Rosmarinic Acid has been shown to dose dependently inhibit migration, adhesion, and invasion of Ls174-T human colon carcinoma cells. Rosmarinic Acid has been documented to increase the melanin content in B16 melanoma cells through activation of protein kinase A. In the same study rosmarinic acid induced the phosphorylation of CRE-binding protein (CREB) and activated cAMP response element (CRE). In the classical complement pathway Rosmarinic Acid inhibited C3-convertase. It also has shown to be an activator of GPR35.[Santa Cruz]
4. Rosmarinic acid is a naturally-occurring phenolic compound with antioxidant and anti-inflammatory properties. This compound inhibits lipid peroxidation of rat liver microsomes by 90% at a concentration of 25 µg/ml.Rosmarinic acid suppresses endotoxin-induced activation of complement and concomitant formation of prostacyclin.Formation of 5-HETE and LTB from human PMNL is inhibited by rosmarinic acid at concentrations of 10-5 to 10-3 M. [caymanchem]

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Company Profile：

 

Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.

We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.

 

 

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Exhibitions:

 

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Products & Packaging：

 

Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.

 

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About  Us 

 

 

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Shipment & Payment：

 

*small quantity: By Fedex, DHL, HKPOST, UPS, TNT or As customers’ requirement

*Bulk order: By air or sea

*Delivery: within 3 days for samples and 10 days for bulk order

 

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Our Markets: 

 

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FAQ

 

1. Are you a trade company or factory

We are a factory with our own trading company.

 

2. How do you control the quality

Our factory is equipped with professional technicians to inspect the quality around production lines. The inspection test would be made every 2 hours to ensure the production conform to quality standard. We also accept BV, SGS, or any third pary inspection.

3. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

 

4. Where is your factory located How can I visit the factory

Our factory located in Hebei, China

 

5. Can I get some samples

Yes, we can supply sample with free, but the shipping cost be paid by our customers.

 

6. How to start orders or make payments

Proforma Invoice will be issued first after confirmation of order, enclosed our bank information. Payment could be done by T/T or .

 

7. How to confirm the product quality before placing order

You can get free samples for some products. You only need to pay the shipping cost or arrange a courier to us and take the samples.

 

8. How do you treat quality complaint

First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.