Sarcosine 107-97-1 203-538-6
sarcosine is an intermediate in the production glycine from dietary consumption of choline. It is used in making toothpastes and biodegradable surfactants. Sarcosine can be found in foods such as vegetables, ham, egg yolks, turkey and legumes. The normal concentrations of sarcosine in human serum and in human urine are 1.4 µM and 1.6 µM respectively.
Sarcosine has been observed to improve treatment of the mental illness known as schizophrenia: 2 g per day consumption of sarcosine (in addition to antipsychotic drug therapy) results in significant additional reductions not only both positive and negative symptoms, but also general psychopathological and neurocognitive symptoms. Sarcosine is thought to work by increasing glycine concentrations in the brain which causes increased NMDA receptor activation. Interestingly, consumption of sarcosine also reduced depressive symptoms in patients with schizophrenia. A clinical study showed sarcosine to be significantly more effective in treating major depression than the established antidepressant drug Citalopram.
Product Name: | Sarcosine |
CAS: | 107-97-1 |
MF: | C3H7NO2 |
MW: | 89.09 |
EINECS: | 203-538-6 |
Melting point | 208-212 °C (dec.)(lit.) |
Boiling point | 165.17°C (rough estimate) |
density | 1.1948 (rough estimate) |
refractive index | 1.4368 (estimate) |
Fp | >100℃ |
storage temp. | Store below +30°C. |
solubility | H2O: 1 M at 20 °C |
pka | 2.21(at 25℃) |
form | Crystals or Powder |
color | Colorless or white to yellow |
PH | 6.1 (100g/l, H2O, 20℃) |
Water Solubility | 1480 g/L (20 ºC) |
Sensitive | Hygroscopic |
Merck | 14,8373 |
BRN | 1699442 |
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