3ALPHA-HYDROXY-7-OX...

3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANICACID

3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANICACID

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1 Gram

FOB Price: USD 120.0000

  • Min.Order :1 Gram
  • Purity: 96%
  • Payment Terms : D/P,T/T

Keywords

3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANICACID 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANICACID 96% 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANICACID

Quick Details

  • Appearance:white power
  • Application:α-Hydroxy-7-oxo-5Β-cholanic acid is a derivative of lithocholic acid, a cholic acid derivative that acts as a TGR5 regulator. Application 3-hydroxy-7-oxo-5-cholanic acid is an intermediate in org
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  • ProductionCapacity:20|Metric Ton|Day
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  • Transportation:sea tranpotation

Superiority:

α-Hydroxy-7-oxo-5Β-cholanic acid is a derivative of lithocholic acid, a cholic acid derivative that acts as a TGR5 regulator.

Application 3-hydroxy-7-oxo-5-cholanic acid is an intermediate in organic synthesis and pharmaceutical research and development, and is an intermediate in the synthesis of choleretic drug ursodeoxycholic acid.

The preparation of chenodeoxycholic acid by oxidation of sodium hypochlorite can obtain high-purity 3a hydroxy-7oxo-5β-cholanic acid reaction temperature controlled at -15 °C, acetic acid is used to adjust the acidity methanol as a solvent, and 3a hydroxy-7-oxo-5β-choranic acid crude product is prepared. The crude product was made into barium salt, and then the barium was removed, and finally recrystallized with methanol and water to obtain high-purity 3a-hydroxy-7-oxo-5β-cholane. Biologically active 7-Ketolithocholicacid (3α-Hydroxy-7-oxo-5β-cholanicacid) is a bile acid that can be absorbed, inhibiting the production of endogenous bile acids and the secretion of bile cholesterol.

Target HumanEndogenousMetabolite

In vitro studies Bileacidsaremaincomponentsofmammalianbile.Theyaresteroidcarboxylicacidsthatsynthesizedfromcholesterolinlivertissue.

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