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Isavuconazonium sulfate CAS 946075-13-4 Active Pharmaceutical Ingredient API
Wuhan Fortuna Chemical Co.,Ltd is a professional integrative chemical enterprise with 18 years exporting experience,which is being engaged in Pharmaceutical and its intermediates, Food and Feed additives, Fine chemicals.
1. guaranteed purity;
2. large quantity in stock;
3. largest manufacturer;
4. best service after shipment with email;
5. high quality & competitive price;
Our company to environmental protection production, safe production as the guidelines. Protecting the environment and public health is our company's code of conduct and guiding principles.
1. Staff are equipped with professional protective equipment.
2. Post warning signs on the workshop.
3. Standardized treatment of three wastes.
Description of Isavuconazonium sulfate from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of Isavuconazonium sulfate |
|
Product Name |
Isavuconazonium sulfate |
CAS NO. |
946075-13-4 |
Apperance |
White to light yellow powder |
Assay |
99.6% |
Pacakge |
1kg/Foil Bag,25kg/Drum/Box |
MOQ |
1kg |
Storage |
Cool and dry place |
Shelf Life |
2 Years |
Brand |
Fortunachem |
Specifications(COA) of High Qulity 99.6% Isavuconazonium sulfate CAS 946075-13-4 Active Pharmaceutical Ingredient API with Good Price
Items |
Specifications |
Results |
Appearance |
White to light yellow powder |
Conform |
Solubility |
easily soluble in water or methanol |
Conform |
Specific rotation |
-11° ~ -20° |
-13° |
Identification |
The infrared absorption spectrum of this product should be consistent with that of the reference substance. |
Conform |
In the chromatogram recorded under the assay, the retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution. |
Conform |
|
Relative substance1 |
S29-ZZ-24≤0.50% |
0.13% |
S29-ZZ-23≤0.10% |
N.D. |
|
S29-ZZ-22≤0.30% |
0.07% |
|
S29-ZZ-29+ S29-ZZ-28≤0.20% |
N.D. |
|
S29-ZZ-27≤0.50% |
0.13% |
|
S29-ZZ-26≤1.0% |
0.48% |
|
S29-ZZ-32≤1.0% |
0.57% |
|
4511≤1.0% |
0.55% |
|
4516≤0.10% |
N.D. |
|
Any other single Impurity≤0.10% |
0.08% |
|
Total Impurities |
2.2% |
|
Residual Solvent |
Methanol≤ 3000ppm |
626ppm |
Ethanol≤ 5000ppm |
936ppm |
|
Isopropyl alcohol≤ 5000ppm |
13ppm |
|
Acetonitrile≤ 410ppm |
N.D. |
|
Dichloromethane≤ 600ppm |
32ppm |
|
Tert-Butanol≤ 3500ppm |
869ppm |
|
Methyl tert-butyl≤ 5000ppm |
68ppm |
|
Ethyl acetate≤ 5000ppm |
697ppm |
|
Pyridine≤ 200ppm |
N.D. |
|
n-Heptane≤ 5000ppm |
N.D. |
|
Relative substance2 |
1633≤0.10% |
0.01% |
|
S29-ZZ-3≤0.30% |
0.06% |
Sulfate |
12.0% ~18.0% |
15.35 |
Water |
≤ 2.0% |
0.3% |
Acid Value |
PH should be 1.3~2.0 |
1.6 |
Residue on Ignition |
≤0.1% |
0.04% |
Heavy Metals |
≤10ppm |
Conform |
2-Butenal |
≤50ppm |
13ppm |
Assay |
94.0% ~102.0% |
96.6% |
Bacterial endotoxin |
The amount of endotoxin in each 1mg of isavuconazole sulfate should be less than 0.3EU |
Conform |
Microbial Limit |
Total aerobic bacteria≤100cfu/g |
≤50cfu/g |
Molds and yeasts≤50cfu/g |
≤50cfu/g |
|
Escherichia coli≤0/g |
N.D. |
|
Conclusion |
QUALIFIED. |
Introduction of Isavuconazonium sulfate.
Isavuconazonium sulfate is a prodrug of isavuconazole, an antifungal agent. It is used to treat serious fungal infections, including invasive aspergillosis and invasive mucormycosis. These infections are typically seen in immunocompromised patients, such as those undergoing chemotherapy, organ transplantation, or those with HIV/AIDS.
Isavuconazonium sulfate is administered intravenously or orally, and once inside the body, it is rapidly converted to its active form, isavuconazole. Isavuconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting cell membrane integrity and leading to the death of the fungal cells.
Application of Isavuconazonium sulfate.
Isavuconazonium sulfate is primarily used in the medical field for the treatment of serious fungal infections. Its main applications include:
Invasive Aspergillosis: This is a severe infection caused by Aspergillus species, which can affect the lungs and other organs. It is particularly dangerous for immunocompromised individuals, such as those undergoing chemotherapy, organ transplants, or those with HIV/AIDS.
Invasive Mucormycosis: This is another serious fungal infection caused by fungi in the order Mucorales. It can affect the sinuses, brain, and lungs, and is also more common in immunocompromised patients.
Isavuconazonium sulfate is administered either intravenously or orally, and it is rapidly converted in the body to its active form, isavuconazole. The active drug works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, thereby disrupting the integrity of the cell membrane and leading to fungal cell death.
FAQ From Wuhan Fortuna Chemical Co.,Ltd |
|
Q |
Can I get a sample for free |
A |
For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
|
|
Q |
How to confirm the product quality before placing orders |
A |
Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
|
|
Q |
What is the payment you accept |
A |
For small and low value order, we accept CreditCard, MaterCard,VISA, and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
|
|
Q |
What is your shipment way |
A |
For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
|
|
Q |
How long is your after-sales service |
A |
We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
|
|
How do you treat quality complaint |
|
A |
We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Isavuconazonium sulfate with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Isavuconazonium sulfate.
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