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Dmpsc Chlorodimethylphenylsilane Dmpsc Chlorodimethylphenylsilane CAS:768- 33-2
[ProductName ]
[CasNo][768- 33-2]
[Molecular formula]C8H11SiCl
[Molecular Weight]170.71
[Physical and Chemical Properties ]
Colorless or light yellow liquid, boiling point 194-198°C, relative density ( 25°C) l.032g/ml, refractive index n/0 I .506-1.51, flash point 61°C, melting point < 0°C. lt's a pharmaceutical intermediate, slightly harmful to water. It is stable at normal temperature and pressure, avoid contacting oxide water and reactive metals. It can be stored in dry environment, keep container sealed and in a dry place.
[Usage] Dimethylphenylchlorosilane is a very important Sterically hindered silane. Its steric hindrance is large, and its derivants are more stable than trimethyl ether under acid and alkali conditions. It is widely used in the synthesis of simvastatin, enteka and other drugs, and has a great development prospect and application space.
Item |
Standard |
Test Results |
|
Identification |
A.H-NMR:Comply with the structure |
Complies |
|
B.LC-MS:Comply with the structure |
Complies |
||
C.The IR spectrum of sample should be identical with that of reference standard; |
Complies |
||
D.HPLC-ESI-MS |
Complies |
||
The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. |
|||
Heavy metals |
≤10 ppm |
<10ppm |
|
Water |
≤1.0% |
0.10% |
|
Sulphated ash |
≤0.5%, determined on 1.0 g. |
0.01% |
|
Related substances |
Unspecified impurities: for each impurity |
≤0.10% |
<0.10% |
Total Impurity |
≤0.5% |
0.18% |
|
Purity |
≥99.0% |
99.70% |
|
Assay |
99.0%~101.0% (anhydrous substance). |
99.80% |
|
Storage |
Preserve in well-closed, light-resistant and airtight containers. |
Complies |
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