cas 6112-76-1 99 ...

cas 6112-76-1 99 % puriy 6-Mercaptopurine monohydrate powder

cas 6112-76-1 99 % puriy 6-Mercaptopurine monohydrate powder

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10 Gram

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  • Min.Order :10 Gram
  • Purity: 99
  • Payment Terms : L/C,T/T,

Keywords

6-Mercaptopurine monohydrate 6-Mercaptopurine monohydrate powder 99% 6-Mercaptopurine monohydrate

Quick Details

  • Appearance:white
  • Application:anti aging
  • PackAge:drum
  • ProductionCapacity:1000|Kilogram|Month
  • Storage:room
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Superiority:

 cas 6112-76-1   99 % puriy 6-Mercaptopurine monohydrate  powder  

MOQ:

10g

Form:

Powder

Colour:

White

Test:

HPLC

Function:

anti cancer

Grade:

Pharm

 

Details:

cas 6112-76-1   99 % puriy 6-Mercaptopurine monohydrate  powder  

Product Name:    6-Mercaptopurine monohydrate
CAS:    6112-76-1
MF:    C5H6N4OS
MW:    170.19
EINECS:    612-090-4

6-Mercaptopurine (6-MP) is an inhibitor of purine synthesis and interconversion. It is rapidly converted to 6-mercaptopurine ribonucleoside-5''-monophosphate, which inhibits phosphoribosyl pyrophosphate (PRPP) amidotransferase, the rate-limiting enzyme in purine synthesis. It also inhibits the conversion of IMP to adenylosuccinic acid and xanthylic acid and blocks AMP formation in vitro. 

6-MP inhibits growth of sarcoma 180, adenocarcinoma E 0771, and adenocarcinoma 755 tumors and reduces the size of leukemia L1210 subcutaneous growths in mice. It also decreases delayed-type hypersensitivity and thyroid inflammation in a guinea pig model of thyroiditis when administered pre- or post-disease onset. Formulations containing mercaptopurine have been used for maintenance therapy in patients with acute lymphoblastic leukemia.

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