cas 871700-17-3 99...

cas 871700-17-3 99% purity Trametinib powder

cas 871700-17-3 99% purity Trametinib powder

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 99
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Trametinib Trametinib powder 99% Trametinib

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  • Appearance:white
  • Application:Artemisia annua is used as antimalarial drugs.
  • PackAge:drum
  • ProductionCapacity:1000|Kilogram|Month
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cas 871700-17-3  99% purity Trametinib powder 

 Product Name:    Trametinib
 CAS:    871700-17-3
MF:    C26H23FIN5O4
MW:    615.39

 

Details:

cas 871700-17-3  99% purity Trametinib powder 

 Product Name:    Trametinib
 CAS:    871700-17-3
MF:    C26H23FIN5O4
MW:    615.39 

Trametinib   is a cancer drug. It is a MEK inhibitor drug with anti-cancer activity.
Trametinib(Mekinist) is a reversible, highly selective, allosteric inhibitor of mitogen-activated extracellular signal regulated kinase 1 (MEK1) and MEK2 activation and kinase activity. MEK proteins are components of the extracellular signal-related kinase (ERK) pathway. In melanoma and other cancers, this pathway is often activated by mutated forms of BRAF which activates MEK.

 Trametinib inhibits activation of MEK by BRAF and inhibits MEK kinase activity. Trametinib inhibits growth of BRAF V600 mutant melanoma cell lines and demonstrates anti-tumor effects in BRAF V600 mutant melanoma animal models.
Mekinist is indicated as monotherapy or in combination with Tafinlar (dabrafenib) for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation.

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