cas 641571-10-0 Ni...

cas 641571-10-0 Nilotinib powder

cas 641571-10-0 Nilotinib powder

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 99
  • Payment Terms : L/C,T/T,

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Nilotinib Nilotinib powder 99% Nilotinib

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  • Appearance:white
  • Application:Artemisia annua is used as antimalarial drugs.
  • PackAge:drum
  • ProductionCapacity:1000|Kilogram|Month
  • Storage:room
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cas 641571-10-0  Nilotinib  powder 

Product Name:    Nilotinib
CAS:    641571-10-0
MF:    C28H22F3N7O
MW:    529.52
EINECS:    700-544-5

 

Details:

cas 641571-10-0  Nilotinib  powder 

Product Name:    Nilotinib
CAS:    641571-10-0
MF:    C28H22F3N7O
MW:    529.52
EINECS:    700-544-5

Nilotinib is a novel drug for targeted cancer therapy and belongs to tyrosine kinase inhibitors for the treatment of patients of chronic myelogenous leukemia (CML). for the treatment of chronic myelogenous leukemia (CML) .

Nilotinib is the developed through the improvement of the molecular structure of imatinib with a stronger selectivity on the BCR-ABL kinase activity. The inhibitory effect of nilotinib on the tyrosine kinase is 30 times as high as that of imatinib. It is capable of suppressing the activity of the imatinib-resistant BCR-ABL mutant kinase while also being able to inhibit the activity of KIT and PDGFR kinase.

With administration twice daily, nilotinib can targeted to the Bcr-Abl protein, interact with it and inhibit the emergence of cancer cells containing abnormal chromosomes. Bcr-Abl protein is produced by cells containing the abnormal Philadelphia chromosome. For patients of CML, this protein is considered to be an important factor for causing the excessive proliferation of cancer-causing white blood cells.

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