GMP Ceftiofur Sodium cas 104010-37-9

Details:

GMP  Ceftiofur Sodium cas 104010-37-9 powder 

 Product: Ceftiofur Sodium 
CAS NUMBER: 104010-37-9
Chemical Formula: C19H16N5O7S3Na
Molecular Weight:545.544  
Solubility: Very soluble in water. 

Uses: It belongs to antibiotic medicines for the treatment of swine bacterial respiratory infection
Ceftiofur sodium is resistant to the antibiotic resistance enzyme beta-lactamase, and has activity against Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. The bactericidal activity of ceftiofur results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins. The PBPs are transpeptidases which are vital in peptidoglycan biosynthesis. Therefore, their inhibition prevents this vital cell wall component from being properly synthesized.

Veterinary Drugs and Treatments:
 Labeled indications for ceftiofur sodium:
1)In cattle for treatment of bovine respiratory disease (shipping fever, pneumonia) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. It is also indicated for treatment of acute bovine interdigital necrobacillosis (foot rot, pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.
2)In swine for treatment/control of swine bacterial respiratory disease (swine bacterial pneumonia) associated with Actinobacillus (Haemophilus) pleuropneumoniae, Pasteurella multocida, Salmonella choleraesuis and Streptococcus suis.
3)In sheep/goats for treatment of sheep/caprine respiratory disease (sheep/goat pneumonia) associated with Mannheimia haemolytica and Pasteurella multocida.
4)In horses for treatment of respiratory infections in horses associated with Streptococcus zooepidemicus. In dogs for the treatment of canine urinary tract infections associated with E. coli and Proteus mirabilis.
5)In day old chicks/poults for the control of early mortality, associated with E. coli organisms susceptible to ceftiofur.