Veliparib Dihydrochloride Abt-888 cas 912445-05-7

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1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: 99
Payment Terms : L/C,T/T,MoneyGram

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Veliparib Veliparib Dihydrochloride powder 99% Veliparib Dihydrochloride

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Appearance:white
Application:Artemisia annua is used as antimalarial drugs.
PackAge:drum
ProductionCapacity:1000|Kilogram|Day
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Veliparib Dihydrochloride Abt-888 cas 912445-05-7

Product Name: Veliparib Dihydrochloride
CAS: 912444-00-9
MF: C13H16N4O.2ClH
MW: 317.218

Details:

Veliparib Dihydrochloride Abt-888 cas 912445-05-7

Product Name: Veliparib Dihydrochloride
CAS: 912444-00-9
MF: C13H16N4O.2ClH
MW: 317.218

Veliparib is a potent PARP1 and PARP2 inhibitor with Ki of 5.2nM and 2.9nM, respectively, inhibiting SIRT2.Phase3.ABT-888 effectively inhibited PARP, and the Ki value of PARP-1 and PARP-2 was 5.2 nM and 2.9nM, respectively.ABT-888 decreased the survival rate of cloned genes in lung cancer H460 cells and inhibited DNA repair.ABT-888 inhibited C41 cells with an EC50 of 2nM.ABT-888 is used in combination with radiation to reduce tumor angiogenesis.

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