GLUCAGON ACETATE GLUCAGON 37 L-Threonine, L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-α-aspartyl-L-seryl-L-arginyl-L-argin yl-L-
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♦ High purity, all above 98.5%, no impurities after dissolution
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Density 1.5± 0.1g /cm3
Molecular formula C153H225N43O49S
Molecular weight 3482.747
Accurate mass 3480.615723
PSA 1564.04000
LogP -6.01
Appearance character powder
Refractive index 1.682
Storage conditions −20°C
stability
This product is a twenty-nine peptide. It's secreted by insulin A cells. In hypoglycemia, its secretion is normal and the plasma half-life is about 3 ~ 6min. It was mainly inactivated in liver, followed by transrenal and hematologic. The effect of zinc glucagon was longer. The release of glucagon in the human body under severe stress is undoubtedly a physiological self-protective effect. For example, after extensive burns, acute myocardial infarction with cardiogenic shock, acute pancreatitis, and surgery, plasma concentrations are significantly elevated. A cell proliferation or tumor of the islets also releases large amounts of glucagon.
Practically insoluble in water and in most organic solvents. It is soluble in dilute mineral acids and in dilute. Practically insoluble in water and in most organic solvents. It is soluble in dilute mineral acids and in dilute solutions of alkali hydroxides.
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