(S)-1-(2,6-Dichloro...

(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol,

(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol,

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1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 99%
  • Payment Terms : T/T,Other

Keywords

(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol, 877397-65-4 99%purity

Quick Details

  • Appearance:White solid
  • Application:intermediate
  • PackAge:according to the need of packing
  • ProductionCapacity:100|Gram|Day
  • Storage:2-8°C
  • Transportation:sea/courier/air

Superiority:

(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Basic information
Product Name:    (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
Synonyms:    BenzeneMethanol,2,6-dichloro-3-fluoro-a-Methyl-, (aS)-;(1S)-1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol;(S)-1-(2,6-dichloro-4-fluorophenyl)ethanol;(1S)-1-(2,6-Dichloro-3-fluorophenyl)ethane-1-ol;(aS)-2,6-Dichloro-3-fluoro-a-methyl-benzenemethanol;-1-(2,6-Dichloro-3-fluorophenyl);(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol;(S)-1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol
CAS:    877397-65-4
MF:    C8H7Cl2FO
MW:    209.04
EINECS:    700-699-9
Product Categories:    Aromatic Ring;Chiral Compounds
Mol File:    877397-65-4.mol

(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Chemical Properties
Boiling point     261.3±35.0 °C(Predicted)
density     1.406±0.06 g/cm3(Predicted)
storage temp.     2-8°C
pka    13.30±0.20(Predicted)
form     Solid
color     White
InChI    InChI=1/C8H7Cl2FO/c1-4(12)7-5(9)2-3-6(11)8(7)10/h2-4,12H,1H3/t4-/s3
InChIKey    JAOYKRSASYNDGH-UFLUHPNLNA-N
SMILES    [C@H](C1C(=CC=C(F)C=1Cl)Cl)(O)C |&1:0,r|
CAS DataBase Reference    877397-65-4

Details:

(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Usage And Synthesis
Uses    (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is an intermediate in the synthetic preparation of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor ( c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
Uses    (S) -1- (2,6-dichloro-3-fluorophenyl) ethanol(C8H7C12FO) is synthesized (R)-3-[l-(2, 6-dichloro-3-fluoro-benzene)- The key intermediate of ethoxy-5- (l-piperidine-4-hydroxy-1 hydrogen-pyrazole-4-hydroxy) -pyrimidine-2-indane. And (R)-3-[l-(2,6-dichloro-3-fluoro-benzene)-ethoxy-5-(l-piperidine-4-hydroxy-1 hydrogen-pyrazole-4-hydroxy) -Pyrimidine-2-indane is a small molecule kinase inhibitor for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) positive for anaplastic lymphohematokinase (ALK).
Uses    (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is an intermediate in the synthetic preparation of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.

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