Acyclovir 9-[(2-Hydroxyethoxy)methyl]guanine CAS:88495-63-0
Product Name: | Acyclovir | Appearance: | White Crystalline Powder |
---|---|---|---|
CAS No.: | 88495-63-0 | Molecular Formula: | C19H28O8 |
ITEMS OF ANALYSIS |
REQUIREMENTS |
RESULT |
Appearance |
A white crystalline powder, odorless |
Confroms |
Solubility |
Freely soluble in ethanol, acetone or chloroform. very slightly soluble in water. |
Confroms |
Specific Optical Rotation | +4.5°~+6.5° |
+5.4° |
TLC |
The principal spot in the chromatogram obtained with the test solution is similar in position, color to the principal spot in the chromatogram obtained with the reference solution |
Confroms |
HPLC |
The retention time of main peak of test and standard are concordant |
Confroms |
Acidity | 3.5~4.5 |
4.2 |
Appearance of Solution |
Solution is clear and not more intensely colored than reference solution 1 |
Confroms |
Water | NMT 0.5% |
0.48% |
Chlorides | Not more pronounced (0.02%) |
Confroms |
Related Substances (HPLC) |
Artemrsinin: NMT 0 5% |
N.A |
Dihydroartemisinin: NMT 1 0% |
N.A |
|
Impurity: NMT 0.2% |
0,04% |
|
Any other impurities: NMT 0.2% |
0.09% |
|
Total impurities NMT 2.0% |
0.13% |
|
Residual on Ignition | NMT01% |
0.07% |
Heavy Metal | NMT 20ppm |
Confroms |
Bacterial Endotoxin | NMT 1.25EU |
Confroms |
Assay (By HPLC) | 98.0%~102.0% |
98.7% |
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