Ivermectin 22,23-dihydroavermectin CAS:70288-86-7
Product Name |
Ivermectin |
Appearance | Light yellow to brown powder |
Assay | 99% |
CAS | 70288-86-7 |
MF | C48H74O14 |
Item |
Specification |
Results |
Appearance |
White or yellowish-white crystalline powder |
Complies |
IR |
Corresponds with that of CRS standard |
Complies |
HPLC |
The retention time for H2Bla and H2Blb coreesponds with that of standard preparation |
Complies |
Specific optical rotation |
-17° ~ -20° |
-17.8° |
Related substances (%) |
Individual impurities(RT1.3-1.5)≤2.5 Any other individual impurities≤1
Total≤5 |
I-1:<0. 05 K:2 . 2 C:0 . 1 A:0 . 6 J:0 . 2 H:0 . 5 D:0 . 1 F:0 . 2 E:0 . 6 I-2: 0 . 2 4.2 |
Ethanol and formamide(%) |
Ethanol≤5.0 Formamide≤3.0 |
4.2 2.6 |
Catalyst(ug/g) |
≤1 |
<1 |
Water(%) |
≤1.0 |
0.28 |
Sulphated ash(%) |
≤0.1 |
0.04 |
Heavy Metal(%) |
≤0.002 |
<0.002 |
Assay(%) (HPLC, Basis on drying) |
H2Bla/(H2Bla+H2Blb)≥90.0 95.0≤H2Bla+H2Blb≤102.0 |
98.1 96.3 |
Conclusion |
Complies with requirements of EP9.0 |
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