CasNo.104121-92-8,2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3,(104121-92-8) Suppliers

1 Kilogram	FOB Price:USD 100.0000 -102.0000

Min.Order :1 Kilogram
Purity: 98%
Payment Terms : T/T,MoneyGram,Other

Keywords

2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3 Eldecalcitol ED-71

Quick Details

Appearance:White powder
Application:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and activity against the cyclin B/CDK1 complex is 1000 times less t...
PackAge:Fiber can/Drum/Bag
ProductionCapacity:100|Kilogram|Day
Storage:Seal and store in a cool and dry place
Transportation:By sea/air/land

Superiority:

1. Product advantages
High purity, all above 98.5%, no impurities after dissolution
We will test each batch to ensure quality
OEM and private brand services designed for free
Various cap colors available
We can also provide MT1 peptide powder
2. Factory advantages
Professional research team
More than 5 doctors in high-tech R&D laboratories
More than 1000 m2 of factory production line to ensure stable supply
More than 1200 factories to manufacture products and control quality
3. Service advantages
24-hour online service
Track package information and update it for customers
Professional sales team
Accept small order service
Redelivery service if detained by customs

Details:

Product Introduction:

Product Name:	Eldecalcitol
CAS:	104121-92-8
MF:	C30H50O5
MW:	490.71
Quality Standard:	Internal Standard
Molecular Structure:

Active vitamin D drugs are a general term for a series of vitamin D2/D3 derivatives, commonly referred to as "calciferol" drugs. These compounds are complex in structure and involve techniques such as photochemistry and microbial transformation. They are difficult to synthesize, sensitive to light and oxygen, and the API in the preparation is microgram-level, and the development threshold is high. Clinically used mainly for the treatment of osteoporosis, secondary hyperparathyroidism and psoriasis.

Eldecalcitol is an analog of the active form of vitamin D, calcitriol, in which the lower ring contains a hydroxypropyl group. The synthesis of eldecalcitol involves the assembly of two units, a fully protected (3S,4S,5R)-oct-1-en-7-yne-3,4,5-triol and a fused bicyclic system, (R)-6- ((1R,3aR,7aR,E)-4-(bromomethylene)-7a-methyloctahydro-1H-inden-1- yl)-2-methylheptan-2-ol, through a Diels-Alder reaction to give fully protected eldecalcitol. The hydroxyl groups are then deprotected to give the parent molecule. Eldecalcitol binds to the vitaminDreceptor 2.7-fold more potently than calcitriol, while only weakly inhibiting serum parathyroid hormone.

Hebei Sankai Chemical Technology Co., Ltd. is a new chemical enterprise integrating the research, manufacturing and supply of chemicals. Located in the beautiful "cattle city" Xingtai, Hebei Sankai Chemical Technology Co., Ltd. is mainly engaged in the research of chemical fertilizer. At the same time, we have made great breakthroughs in food, feed additives, cosmetics, dyes and industrial chemicals. Our company spirit of "integrity management, quality control, customer first" belief, at home and abroad enjoy high reputation.