CasNo.646-01-5,3-METHYLTHIOPROPIONIC ACID,(646-01-5) Suppliers

1 Kilogram	FOB Price:USD 50.0000 -100.0000

Min.Order :1 Kilogram
Purity: 98%
Payment Terms : T/T,MoneyGram,Other

Keywords

3-METHYLTHIOPROPIONIC ACID 3-methylsulfanylpropanoic acid EINECS 211-460-9

Quick Details

Appearance:White powder
Application:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and activity against the cyclin B/CDK1 complex is 1000 times less t...
PackAge:fiber can
ProductionCapacity:100|Metric Ton|Month
Storage:Seal and store in a cool and dry place
Transportation:By sea/air/land

Superiority:

1. Product advantages
High purity, all above 98.5%, no impurities after dissolution
We will test each batch to ensure quality
OEM and private brand services designed for free
Various cap colors available
We can also provide MT1 peptide powder
2. Factory advantages
Professional research team
More than 5 doctors in high-tech R&D laboratories
More than 1000 m2 of factory production line to ensure stable supply
More than 1200 factories to manufacture products and control quality
3. Service advantages
24-hour online service
Track package information and update it for customers
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Accept small order service
Redelivery service if detained by customs

Details:

Description 3- (Methylthio) propionic acid is an intermediate in methionine metabolism.
Related categories
Signal Pathways>>Anti Infection>>Fungi
Research Fields>>Cancer
In vitro studies designed to evaluate the relative toxicity of dietary amino acids, methionine has always been proven to be the most toxic amino acid. 3-Methylthiopropionate is an intermediate in the degradation and metabolism of methionine in rat and monkey livers in vitro. This pathway seems to be the main part of in vitro methionine oxidation [1]. The culture of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid, and its amount was directly related to the concentration of methionine in the culture medium. The first intermediate in this pathway can be keto acid, which is then oxidized and decarboxylated to 3-methylthiopropionic acid [2]. The purified 3-MTPA has antifungal activity in the assay using F.oxysporum as a model fungus. Daily measurements of shoot and root length showed that for partially purified extracts, seed germination and root and shoot development were severely inhibited at concentrations above 12mg [3]. Ethyl 3-methylthiopropionate has potential anticancer properties by inducing differentiation in well differentiated colon cancer cells. Treatment of RCM-1 cells with 0.25 and 2mM doses of 3-methylthiopropionate ethyl ester for 4 days gradually increased the percentage of area occupied by the pipeline structure relative to the control substance, and also caused an increase in the number and maximum diameter of conduits in each culture plate [4].
Cell experiments were conducted by laying RCM-1 cells on a 35-mm plastic culture plate. 24 hours after inoculation, the cells were treated with 3-methylthiopropionate ethyl ester in 2mL 10% FBS-RPMI+F-12 for 4 days, and were counted using a blood cell counter after digestion with 0.25% trypsin and 1mM EDTA trypsin. [4]