Miglitol

Details:

Product Introduction:

pharmacological action 
This product is a second-generation glucosidase inhibitor. This product is a small molecule compound with a structure similar to glucose. In the process of food digestion, α- Glucosidases (including maltase, isomaltase, sucrase, glucoamylase, etc.) can hydrolyze polysaccharides and oligosaccharides in food into monosaccharides (including glucose). α- Glycosidase inhibitors can delay the production and absorption of glucose, thus alleviating the postprandial hyperglycemia and its rapid changes in blood glucose in diabetes patients. This product mainly acts on the small intestine and has little impact on the hydrolysis of carbohydrates in the colon. Adverse reactions in the gastrointestinal tract secondary to the fermentation of unabsorbed sugars are less common than acarbose.
Pharmacokinetics
This product is more easily absorbed in the small intestine than acarbose, and the absorption degree of oral administration decreases with increasing dosage. The bioavailability of 25mg orally administered drug is 100%, while the bioavailability of 100mg orally administered drug is about 50-70%, and absorption can reach saturation at higher doses. Its protein binding rate is less than 4%, and its distribution volume is 0.18L/kg. Less metabolized in the body, over 95% is excreted from urine in its original form. When the dosage exceeds 25mg, due to incomplete absorption, a small amount of medication can be reabsorbed through urine.

Hebei Sankai Chemical Technology Co., Ltd. is a new chemical enterprise integrating the research, manufacturing and supply of chemicals. Located in the beautiful "cattle city" Xingtai, Hebei Sankai Chemical Technology Co., Ltd. is mainly engaged in the research of chemical fertilizer. At the same time, we have made great breakthroughs in food, feed additives, cosmetics, dyes and industrial chemicals. Our company spirit of "integrity management, quality control, customer first" belief, at home and abroad enjoy high reputation.