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Enzalutamide 915087-33-1 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-methylbenzamide
Jinlan Pharm is professional producer and supplier for Enzalutamide.We have completed commercial quantity production of Enzalutamide with DMF and Local GMP.If you want to order Enzalutamide, please let us know.
Description:
API name: Enzalutamide
Certificates: GMP DMF
CAS No.: 915087-33-1
Chemical name:
N-methyl-4-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-2-fluorobenzamide;
Enzalutamide;
4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide;
4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-methylbenzamide;
Formula: C21H16F4N4O2S
Structure:
Usage:
Enzalutamide is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has also been shown to induce tumor cell apoptosis, and has no agonist activity. Enzalutamide is a candidate for the treatment of castration-resistant prostate cancer.
Specification Sheet:
Item |
Specification |
Appearance |
White or off-white powder |
Identification |
IR: corresponding to the reference |
HPLC: corresponding to the reference |
|
Clarity and color of solution |
Should conform the requirement |
Water |
≤5.0% |
Loss on drying |
≤0.5% |
PH |
4.0~10.0 |
Heavy metals |
≤20ppm |
Related substances |
Any unknown impurity ≤0.1% |
Total impurities ≤1.0% |
|
Residual solvent |
Ethanol≤5000ppm |
Methanol≤3000ppm |
|
Microbial limit |
Total aerobic bacterial count ≤100CFU/g |
Total mold and yeast≤100CFU/g |
|
Assay |
98.0%~102.0% |
HS Code: 2933990090
Jinlan Pharm is professional producer and supplier for Enzalutamide.We have completed commercial quantity production of Enzalutamide with DMF and Local GMP.If you want to order Enzalutamide, please let us know.
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