Olaparib 763113-22-0 AZD2281(olaparib)/AZD-2281
Jinlan Pharm is professional producer and supplier for Olaparib.We have completed commercial quantity production of Olaparib with DMF and Local GMP.If you want to order Olaparib, please let us know.
Description:
API name: Olaparib
Certificates: GMP DMF
CAS No.: 763113-22-0
Chemical name:
1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]piperazin;
OlaparidAZD2281;
4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one;
4-[[3-[[4-(CycloprChemicalbookopylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]Methyl]-1(2H)-phthalazinone;
AZD2281(olaparib)/AZD-2281;
AZD2281(olaparib);
4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Formula: C24H23FN4O3
Structure:
Usage:
Olaparib (AZD-2281) is a targeted therapy for cancer. Olaparib is a PARP inhibitor, inhibiting poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair. Olaparib acts against cancers in people with hereditary BRCA1 or BRCA2 mutations, which include some ovarian, breast, and prostate cancers. In December 2014, olaparib was approved for use as a single agent by the EMA and the FDA.
Specification Sheet:
Item |
Specification |
Appearance |
White or off-white powder |
Identification |
IR: corresponding to the reference |
HPLC: corresponding to the reference |
|
Clarity and color of solution |
Should conform the requirement |
Water |
≤5.0% |
Loss on drying |
≤0.5% |
PH |
4.0~10.0 |
Heavy metals |
≤20ppm |
Related substances |
Any unknown impurity ≤0.1% |
Total impurities ≤1.0% |
|
Residual solvent |
Ethanol≤5000ppm |
Methanol≤3000ppm |
|
Microbial limit |
Total aerobic bacterial count ≤100CFU/g |
Total mold and yeast≤100CFU/g |
|
Assay |
98.0%~102.0% |
HS Code: 2933990090
Jinlan Pharm is professional producer and supplier for Olaparib.We have completed commercial quantity production of Olaparib with DMF and Local GMP.If you want to order Olaparib, please let us know.
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