Afatinib 439081-18-2 (SChemicalbook)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dim;Afatinib(cis-transisomerismtautomers)
Jinlan Pharm is professional producer and supplier for Afatinib.We have completed commercial quantity production of Afatinib with DMF and Local GMP.If you want to order Afatinib, please let us know.
Description:
API name: Afatinib
Certificates: GMP DMF
CAS No.: 439081-18-2
Chemical name:
N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;
(SChemicalbook)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dim;Afatinib(cis-transisomerismtautomers);
Formula: C24H25ClFN5O3
Structure:
Usage:
Afatinib is an anilino-quinazoline that irreversibly inhibits EGFR and HER2 kinase activity.
Specification Sheet:
Item |
Specification |
Appearance |
White or off-white powder |
Identification |
IR: corresponding to the reference |
HPLC: corresponding to the reference |
|
Clarity and color of solution |
Should conform the requirement |
Water |
≤5.0% |
Loss on drying |
≤0.5% |
PH |
4.0~10.0 |
Heavy metals |
≤20ppm |
Related substances |
Any unknown impurity ≤0.1% |
Total impurities ≤1.0% |
|
Residual solvent |
Ethanol≤5000ppm |
Methanol≤3000ppm |
|
Microbial limit |
Total aerobic bacterial count ≤100CFU/g |
Total mold and yeast≤100CFU/g |
|
Assay |
98.0%~102.0% |
HS Code: 2934999090
Jinlan Pharm is professional producer and supplier for Afatinib.We have completed commercial quantity production of Afatinib with DMF and Local GMP.If you want to order Afatinib, please let us know.
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