Axitinib 319460-85-0 l-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
Jinlan Pharm is professional producer and supplier for Axitinib.We have completed commercial quantity production of Axitinib with DMF and Local GMP.If you want to order Axitinib, please let us know.
Description:
API name: Axitinib
Certificates: GMP DMF
CAS No.: 319460-85-0
Chemical name:
N-METHYL-2-{[3-((E)-2-PYRIDIN-2-YLVINYL)-1H-INDAZOL-6-YL]SULFANYL}BENZAMIDE;
N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;
l-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide;
Benzamide,N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;
Formula: C22H18N4OS
Structure:
Usage:
Axitinib is a small molecule tyrosine kinase inhibitor. It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models and has shown partial responses in clinical trials with renal cell carcinoma.
Specification Sheet:
Item |
Specification |
Appearance |
White or off-white powder |
Identification |
IR: corresponding to the reference |
HPLC: corresponding to the reference |
|
Clarity and color of solution |
Should conform the requirement |
Water |
≤5.0% |
Loss on drying |
≤0.5% |
PH |
4.0~10.0 |
Heavy metals |
≤20ppm |
Related substances |
Any unknown impurity ≤0.1% |
Total impurities ≤1.0% |
|
Residual solvent |
Ethanol≤5000ppm |
Methanol≤3000ppm |
|
Microbial limit |
Total aerobic bacterial count ≤100CFU/g |
Total mold and yeast≤100CFU/g |
|
Assay |
98.0%~102.0% |
HS Code: 2933990090
Jinlan Pharm is professional producer and supplier for Axitinib.We have completed commercial quantity production of Axitinib with DMF and Local GMP.If you want to order Axitinib, please let us know.
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