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Simvastatin 79902-63-9 79902-63-9 Simvastatin
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Product Name: | Simvastatin |
Synonyms: | (1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste;7-beta,8-beta(2s*,4s*),8a-beta))-alph;[1S-[1α,3α,7β,8β(2S^<*>^,4S^<*>^),8αβ]-2,2-Dimethylbutanoic acid 1,2,3,7,8,8α-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-y1)ethyl]-1-naphthyl ester;Lodaiès;[(1S,3R,7R,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-oxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoat;Butanoic acid, 2,2-dimethyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro- 4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1-alpha,3-alpha,7- beta,8-beta(2S*,4S*),8a-beta));[8-[2-(4-Hydroxy-6-oxo-tetrahydropyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]2,2-dimethylbutanoate;2,2-Dimethylbutanoic acid (1S)-1,2,3,7,8,8aα-hexahydro-3β,7α-dimethyl-8α-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]naphthalen-1β-yl ester |
CAS: | 79902-63-9 |
MF: | C25H38O5 |
MW: | 418.57 |
EINECS: | 616-751-8 |
Product Categories: | MOBIC;Chiral Reagents;Inhibitors;HMG-CoA reductase;Heterocycles;API;Antibiotics;APIs;Simvastatin;Intermediates & Fine Chemicals;Pharmaceuticals;API's |
Mol File: | 79902-63-9.mol |
Simvastatin Chemical Properties |
Melting point | 127-132 °C (lit.) |
alpha | D25 +292° (c = 0.5% in acetonitrile) |
Boiling point | 564.9±50.0 °C(Predicted) |
density | 1.11±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMSO: ≥20mg/mL |
pka | 13.49±0.40(Predicted) |
form | solid |
color | white |
optical activity | [α]/D +275±25°, c = 1 in acetonitrile |
Merck | 14,8539 |
Stability: | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months. |
CAS DataBase Reference | 79902-63-9(CAS DataBase Reference) |
NIST Chemistry Reference | Simvastatin(79902-63-9) |
EPA Substance Registry System | Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester (79902-63-9) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-24/25 |
WGK Germany | 2 |
RTECS | EK7798000 |
HS Code | 29322090 |
Hazardous Substances Data | 79902-63-9(Hazardous Substances Data) |
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