Imatinib Manufactur...

Imatinib Manufacturer/High quality/Best price/In stock CAS NO.152459-95-5
Imatinib Manufacturer/High quality/Best price/In stock CAS NO.152459-95-5

Imatinib Manufacturer/High quality/Best price/In stock CAS NO.152459-95-5

Min.Order / FOB Price:Get Latest Price

100 Gram

FOB Price:USD 10.0000 -100.0000

  • Min.Order :100 Gram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,MoneyGram

Keywords

Hot sale Imatinib 152459-95-5 C29H31N7O

Quick Details

  • Appearance:White powder
  • Application:API
  • PackAge:1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag) 2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 51
  • ProductionCapacity:50|Metric Ton|Month
  • Storage:Store in dry, dark and ventilated place
  • Transportation:EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEADHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU serviceSea shipping for quantity over 500KG; And air shipping is available f

Superiority:

1. We can provide customers with "one-stop"packaging service,from research,development,production,export and so on
2. Powerful R&D strength let our technology in a leading level,forever,in turn,to provide customers with better service .
3. We have ISO&SGS certificate which let the customers more satisfied and rest assured.
4. More than 19 years of export experience,we can provide customers with more professional service.
5. Mix and different products in ONE PCL,increase the working efficiency for customers.
6. Headquartered in Shanghai, Shanghai is one of the world's largest port, convenient for the customes provide logistics services.

 FAQ

Q: How to start orders or make payments
A:You can send our your Purchase order(if your company has), or just send a simple confirmation by email, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly. for payment can also be by ,money gram ,bitcoin ,that is very easy

Q: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q: What's your MOQ
A:For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts from 100g and 1kg.

Q: Is there a discount
A: Yes, for larger quantity, we always support with better price.

Q:How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we
will send you free goods for replacement or refund your loss.

Q:How to contact us
You can choose your interested products and send inquiry to us.
You can dial our telephone directly, you will get our reply.
Send Email to us.

Q:what is the shipping way
A: for small order ,we ship by air express ,like Fedex, TNT,DHL,EMS ,
for large order ,we can send by air to the air port and send by sea to the sea port

Details:

Xinhao medicine technology (hubei) co. LTD.is located in Wuhan, Hubei Province. The company specializes in the production of organic intermediates, pharmaceutical intermediates, silicones, fluorine, flavors and fragrances intermediates, and has more than 3,000 pharmaceutical intermediates. In addition to catalogues, we also offer customized synthesis and custom production services ranging in size from grams to kilograms to tons. The company has its own quality control laboratory, with high-performance liquid chromatography, gas chromatography, spectrophotometer and other complete testing equipment, can be confirmed before leaving the factory. We also have a professional sales team that provides pre-sales and after-sales services 24 hours a day, and your enquiries or questions will be processed within 12 hours. Customer satisfaction and long-term cooperation are our ultimate goal, and we are committed to helping our customers with our quality products. For HPLC, GCMS, NMR and COA of product test data, please feel free to contact us.  

 

Name

Imatinib

EINECS 604-855-6
CAS No. 152459-95-5 Density 1.256 g/cm3
PSA 86.28000 LogP 4.61210
Solubility N/A Melting Point 113°C
Formula C29H31N7O Boiling Point 451°C
Molecular Weight 493.611 Flash Point 196°C
Transport Information N/A Appearance off white powder
Safety 24/25 Risk Codes R23/24/25; R40; R48/23/24; R51/53
Molecular Structure Molecular Structure of 152459-95-5 (Imatinib) Hazard Symbols T,N 

Synonyms

 

 

 

  Introduction of Imatinib

 

 

 

 

 Properties of Imatinib

 

 

 

 

 

 

  

 

 

  

Structure Descriptors of Imatinib

 

 

 

 

 

 

 Uses of Imatinib

 

 

alpha-(4-Methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl amino)-p-tolu-p-toluidide;4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide;

 

  Imatinib is one kind of white to off-white crystalline or pale yellow powder. The IUPAC Name of this chemical is 4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide. Besides, Imatinib belongs to Molecular Targeted Antineoplastic;Pharmaceutical intermediate;Imatinib. In addition, the Classification Code of this chemical is Antineoplastic; Antineoplastic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors. Imatinib is very soluble in water at pH < 5.5 (mesylate salt). It should be stored at refrigerator.

 

 Physical properties about Imatinib are:
(1)Index of Refraction:  1.671; (2)Surface Tension:  63.6 dyne/cm; (3)Density:  1.255 g/cm3; (4)H bond acceptors:  8; (5)H bond donors:  2; (6)Freely Rotating Bonds:  6; (7)Polar Surface Area:  68.7 Å2; (8)Index of Refraction:  1.671; (9)Molar Refractivity:  147.09 cm3; (10)Molar Volume:  393 cm3; (11)XLogP3-AA: 3.5; (12)H-Bond Donor: 2; (13)H-Bond Acceptor: 7; (14)Rotatable Bond Count: 7; (15)Tautomer Count: 6; (16)Exact Mass: 493.259009; (17)MonoIsotopic Mass: 493.259009; (18)Topological Polar Surface Area: 86.3; (19)Heavy Atom Count: 37; (20)Formal Charge: 0; (21)Complexity: 706; (22)Isotope Atom Count: 0; (23)Defined Atom Stereocenter Count: 0; (24)Undefined Atom Stereocenter Count: 0; (25)Defined Bond Stereocenter Count: 0; (26)Undefined Bond Stereocenter Count: 0; (27)Covalently-Bonded Unit Count: 1; (28)Feature 3D Acceptor Count: 3; (29)Feature 3D Donor Count: 2; (30)Feature 3D Cation Count: 3; (31)Feature 3D Ring Count: 5; (32)Effective Rotor Count: 9.2; (33)Conformer Sampling RMSD: 1.

 

  (1)SMILES: O=C(Nc3ccc(c(Nc2nc(c1cccnc1)ccn2)c3)C)c4ccc(cc4)CN5CCN(CC5)C
InChI: InChI=1/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
(2)InChIKey: KTUFNOKKBVMGRW-UHFFFAOYAJ
(3)Std. InChI: InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
(4)Std. InChIKey: KTUFNOKKBVMGRW-UHFFFAOYSA-N

 

 Imatinib is used in chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies. Imatinib (originally STI571) is a drug used to treat certain cancers. It is the first member of a new class of agents that act by inhibiting particular tyrosine kinase enzymes, instead of non-specifically inhibiting rapidly dividing cells.

Article Data 82

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