(S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER RO-18-0647 Orlistat(synthetase/compound)
safety API losing weight raw material high purity orlistat 99% powder
Specification
Product Name: Orlistat 99% |
Raw material: Compound, fermentation |
Appearance: White Fine Powder |
Specification: 99% |
Test Method: HPLC |
CAS No. / M.F. / M.W. : 96829-58-2/ C29H53NO5 / 495.73 |
Orlistat is a potent and long-acting specific inhibitor of gastrointestinal lipase, by directly blocking the body's absorption of fat in the food intake of energy consumption and fat than once, natural reduction of body fat, so as to achieve the purpose of weight loss.
It is safe to lose weight, the active ingredient does not enter the blood circulation, do not act on the central nervous system, with fewer side effects, no dizziness, palpitation, insomnia, dry mouth, and so on.
Function
1. Orlistat is used with a low-calorie diet to help you lose weight and to maintain your weight after weight loss;
2. Orlistat is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the fat you eat from being absorbed and digested. This undigested fat is then removed in your bowel movements .
Application
1. Used as a pharmaceutical intermediates;
2. Orlistat is currently the best-selling weight loss products.
API(Active Pharmaceutical Ingredient)
Item |
Standard |
|
Structural data confirmation |
1. H-NMR: The data of structure are identical with reference standard |
|
2. HPLC-MS: Ensure the molecular weight of main peak and fragment peak are identical with reference standard |
||
3. IR:The data of IR are identical with that of reference standard |
||
Purity(HPLC) |
≥99.0% |
|
Related impurities |
Specific single impurity |
Meets EP/USP/BP standards |
Non-specific single impurity |
≤0.10% |
|
Total Impurities |
≤0.50% |
|
Crystal form |
Meets EP/USP/BP standards |
|
Loss on drying |
≤1.0% |
|
Water |
≤1.0% |
|
Inorganic salt |
≤0.1% |
|
Heavy metals |
≤10 ppm |
|
Assay |
98.0%~102.0%(According to EP/USP/BP standards) |
|
Microbiological Analysis |
||
Total plate count |
≤1000cfu/g |
|
Yeast and Moulds |
≤100cfu/g |
|
E. Coli. |
Absent |
|
Salmonella |
Absent |
|
S.aureus |
Absent |
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