cas 31431-39-7 Mebendazole powder

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1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: 99
Payment Terms : L/C,T/T,

Keywords

Mebendazole Mebendazole powder 99% Mebendazole

Quick Details

Appearance:white
Application:Artemisia annua is used as antimalarial drugs.
PackAge:drum
ProductionCapacity:1000|Kilogram|Day
Storage:room
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cas 31431-39-7 Mebendazole powder

Product Name:	Mebendazole
CAS:	31431-39-7
MF:	C16H13N3O3
MW:	295.29
EINECS:	250-635-4

Details:

What is Mebendazole

Mebendazole is a broad-spectrum anthelmintic that is active against both larval and adult stages of nematodes selectively binding the β-subunit of tubulin, thereby inhibiting intestinal microtubule synthesis in the parasite (IC50 = 0.19 μM for Giardia in vitro). As a tubulin-binding agent, mebendazole also possesses antitumor properties, inducing apoptosis of various human carcinomas both in vitro and in vivo, thus preventing their growth and migration. Furthermore, mebendazole has been used to inhibit hedgehog signaling in cancer cells via suppression of the formation of the primary cilium, a microtubule-based organelle that functions as a signaling hub for hedgehog pathway activation. Additionally, mebendazole has been shown to stabilize the transcriptional activator HIF-1α and its downstream targets, abrogating oxidative neuronal death in primary neurons.

Mebendazole function

For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.

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