cas 163222-33-1 99%...

cas 163222-33-1 99% Ezetimibe powder

cas 163222-33-1 99% Ezetimibe powder

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 99
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Ezetimibe Ezetimibe powder 99% Ezetimibe

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  • Appearance:white
  • Application:Artemisia annua is used as antimalarial drugs.
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  • ProductionCapacity:1000|Kilogram|Day
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cas 163222-33-1 99% Ezetimibe powder 

Product Name: Ezetimibe
CAS: 163222-33-1
MF: C24H21F2NO3
MW: 409.43
EINECS: 682-606-0

 

Details:

What is Ezetimibe

 Ezetimibe is ananti-hyperlipidemic drug used for lowering the plasma cholesterol levels. It is indicated as an adjunctive therapy to diet for the reduction of high-level total-C, LDL-C, and ApoB in patients suffering primary (heterozygous familial and non-familial) hypercholesterolemia. It is also used in combination therapy with HMG-CoA reductase inhibitors. Ezetimibe does not inhibit the cholesterol synthesis in the liver, or increase bile acid excretion. It takes effect throughacting at the brush border of the small intestine and inhibiting the absorption of cholesterol, further leading to a decrease in the delivery of intestinal cholesterol to the liver. This causes a reduction of hepatic cholesterol stores and an increase in clearance of blood cholesterol.

Ezetimibe function

Ezetimibe as the first hypolipidemic drug to act by blocking the absorption of dietary cholesterol. This drug was discovered by Schering-Plough and is codeveloped and co-marketed by Merck and Schering-Plough for the treatment of hypercholesterolemia and also two less common forms of hyperlipidemia: homozygous familial hypercholesterolemia and homozygous sitosterolemia.

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