cas 1420477-60-6 ...

cas 1420477-60-6 Acalabrutinib powder

cas 1420477-60-6 Acalabrutinib powder

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99
  • Payment Terms : L/C,T/T,

Keywords

Acalabrutinib Acalabrutinib powder 99% Acalabrutinib

Quick Details

  • Appearance:white
  • Application:Artemisia annua is used as antimalarial drugs.
  • PackAge:drum
  • ProductionCapacity:1000|Kilogram|Day
  • Storage:room
  • Transportation:

Superiority:

cas  1420477-60-6  Acalabrutinib powder 

Product Name: Acalabrutinib
CAS: 1420477-60-6
MF: C26H23N7O2
MW: 465.51
EINECS: 814-272-0

 

Details:

What is Acalabrutinib
Acalabrutinib (ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.


Acalabrutinib function
Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL).

View All
Visit Store

You Might Also Like

Related Searches

Contact Supplier

Confirm to collect the product to my collection?

OKCancel

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View