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Lemairamin powde 29946-61-0 supplement Lemairamin powder
Product name |
Lemairamin |
Other name |
2-Propenamide, N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-, (2E)-; Lemairamin (WGX-50) |
CAS No. |
29946-61-0 |
Molecular formula |
C19H21NO3 |
Molecular weight |
311.37 |
Purity |
98.0% |
Appearance |
White to off-white powder |
Application |
Dietary Supplement Raw Material |
Features
(1) Anti-inflammatory activity: WGX-50 exhibits significant anti-inflammatory activity, which makes it a promising candidate for the treatment of inflammatory diseases.
(2) Neuroprotective effect: WGX-50 has been proven to have a neuroprotective effect, protecting neurons from damage and preventing neurodegenerative diseases.
(3) Anti-aging effect: WGX-50 has been found to have significant anti-aging effects on the skin, such as reducing wrinkles and improving skin elasticity.
(4) Source of Lemairamin: In addition to the natural compounds extracted from plant prickly ash, there are currently more synthetic compounds for various applications and are more suitable for the market.
Application
Lemairamin is an amide compound extracted from the bark of Zanthoxylum bungeanum plant. As an agonist of the α7 nicotinic acetylcholine receptor (α7nAChR), it reduces neuroinflammation in Alzheimer's disease and is fully synthetic. Wgx50 has shown encouraging results in preclinical studies, including inhibiting Aβ-induced neuronal apoptosis, reducing neuronal calcium toxicity, reducing the accumulation of Aβ oligomers in the cerebral cortex, and improving cognitive performance in mice.
Product introduction
Lemairamin or Wgx50 is a natural compound extracted from Sichuan peppers that has shown promising results in preventing and treating Alzheimer's disease. Studies have found that it can inhibit Aβ-induced neuronal apoptosis, reduce neuronal calcium toxicity, and reduce the accumulation of Aβ oligomers in the cerebral cortex. Additionally, wgx50 has been shown to improve cognitive performance in mice. Research shows that wgx50 has the potential to prevent protein-protein assembly between amyloid molecules. Overall, wgx50 has potential as a therapeutic for Alzheimer's disease and may provide new avenues for the development of drugs targeting Aβ oligomers. However, further research is needed to investigate its efficacy and safety in humans.
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