High Purity Synephrine hydrochloride Powder CAS 5985-28-4

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Synephrine can be used as a pressor drug, for shock, for heart failure, for the treatment of bronchial asthma and base blood pressure during surgery and anesthesia, collapse and shock, body and position hypotension, etc.; α-adrenoceptor agonist, Vasoconstrictors, etc.

1. Effects on the cardiovascular system The intravenous injection of citrus aurantium, citrus aurantium decoction, citrus aurantium extract, citrus aurantium injection and its active ingredient synephrine hydrochloride can significantly enhance various myocardial contractility properties of anesthetized dogs. The index of pumping function has the effect of strengthening the heart, constricting blood vessels, increasing the total peripheral resistance, and increasing the left ventricular pressure and arterial blood pressure. Modern studies have also confirmed that Citrus aurantium can increase the tension of rabbit aorta in a concentration-dependent manner, and make the aortic smooth muscle contract.

2. The effect on weight loss Synephrine hydrochloride is used as a weight loss accelerator, and its mechanism of action is to stimulate β-3 adrenergic receptors to cause lipid decomposition and subsequent thermogenesis. Most dietary supplements containing synephrine HCL also contain various other ingredients, mainly caffeine, salicylic acid, and ephedrine. The combination of the above-mentioned multiple chemical components can improve the weight-loss effect of synephrine hydrochloride. Taking rats as the research object, repeated oral administration of commercially available lime hydroalcoholic extract with standardized synephrine hydrochloride content, evaluating its food intake and cardiovascular function, found that lime extract can reduce food intake and body weight gain, The electrocardiograms of animals in the experimental group were abnormal.

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