China Cancer Treatment Oxaliplatine API Powder CAS 61825-94-3 Oxaliplati

Details:

Product introduction:

Product Name:	Oxaliplatin
Synonyms:	[SP-4-2-(1R-TRANS)]-(1,2-CYCLOHEXANEDIAMINE-N,N')[ETHANEDIOATA(2-)-O,O']PLATINUM;OXALIPLATIN;trans-l-diaminocyclohexane oxalatoplatinum;(1,2-cyclohexanediamine-n,n’)(ethanedioato(2-)-o,o’)-platinu(sp-4-2-(1r-tr;1-ohp;oxalato(1r,2r-cyclohexanediammine)platinum(ii);oxalatoplatin;[SP-4-2-(1R-trans)]-(1，2-Cyclohexanediamine-N，N，)[ethanedioato(2-)-O，O’Jplatinum
CAS:	61825-94-3
MF:	C8H12N2O4Pt
MW:	395.28
EINECS:	621-248-1
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Antineoplastic;Inhibitors;APIs;Amines;Heterocycles;chemical reaction,pharm,electronic,materials;PRAXILENE;API;61825-94-3
Mol File:	61825-94-3.mol

Eloxatin was launched in France for second-line treatment of metastatic colorectal cancer. Oxaliplatin is a second generation platinum drug prepared in three steps from either k2tCl4 or K2Ptl4. It has an antitumor spectrum similar to cisplatin, however, it is more effective against L1210 leukemia and cisplatin resistant L1210. It is also effective against B16 melanoma but has a dose limiting toxicity of peripheral sensory neuropathy that is reversible upon cessation of the drug. The (R,R)- enantiomer has greater activity than the (S,S)-isomer but this is tumor line dependent, e.g., there was no difference found for P-388 or Sarcoma 180. Clinical drug administration based on circadium timing showed it was better tolerated when given 16 h after the onset of light. Oxaliplatin binds to guanineN7 and can lead to bidentate chelation that results in the bending of DNA. This feature is recognized by high mobility group proteins (HMG) which impedes repair reactions and stops replication and transcription.

Detailed Photos

Uses:

Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.

Packaging & Shipping

Company Profile

Hebei Nengqian Chemical Import&Export Co., Ltd was established in 2015. It is a high-tech professional and technological enterprise integrating R & D, production, and sales. 

Longilat 's main products are food additives, plant extracts, cosmetic raw materials, feed additives, animal extract, amino acids and vitamins. Most of our products are derived from natural plants. Marketing services are available in many countries around the world. 

FAQ

1.Can I get some samples
Yes, usually a 10-20g sample.

2.What's your MOQ
Our MOQ is flexible, usually 1kg-10kg for a trial order is acceptable.

3. Is there a discount
Of course, welcome to contact us. Price would be different based on different quantities. For bulk quantity, we will have a discount for you.

4. How to deliver the goods
≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.

5. What is the shelf life for the products
Most products shelf life 24-36 months. 

6. What's your delivery time
Usually, shipment will be made within 7-15 days against confirmed order.

7. How about the validity of the offer  
Usually, our offer is valid for 1 week. However, validity might vary between different products.