Kaempferol 3-O-arabinoside

Min.Order / FOB Price:Get Latest Price

10 Milligram	Negotiable

10 Milligram

Negotiable

Min.Order :10 Milligram
Purity: ≥98%
Payment Terms : T/T

Keywords

Kaempferol 3-O-arabinoside 99882-10-7 standard supplier in China

Quick Details

Appearance:detailed see specifications
Application:analysis,activity test,Botanical Reference Materials,Standard materials
PackAge:According to the clients requirement.
ProductionCapacity:1|Metric Ton|Day
Storage:Store at 2~8°C
Transportation:by air or by ocean shipping

Superiority:

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine，Traditional Chinese Medicine), Natural Active Pharmaceutical Ingredients worldwide. From small quantities for R&D or reference standard, to large quantities for customizing or manufacturing, Biopurify emphasizes on consistent and reliable services for his customers.
With excellent quality products and good service, we have clients from more than dozens countries and regions, and we pride ourselves in providing our customers with a total satisfaction experiences.
We are doing our best to be your reliable partner for high quality Phytochemicals and Reference Standards from china.

Our main services:
A. Supply active ingredients and reference standards ofTraditional Chinese Medicine, from mgs to kgs scale.
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR, CM and PD services from lab scale, pilot scale to commercial scale(GMP is also available)
E.Traditional Chinese Medicine compounds library

1.Provide traditional Chinese medicine reference materials and natural active ingredients;
2.More than 2200 compounds are available for selection, continuously building high-quality natural product libraries for drug research and development;
3.Provide various screening libraries and more inhibitor products;
4.Provide separation and structural determination of natural products;
5.Laboratory scale pilot to commercial scale collaborative research and process development services.More than 180 experiences in phytochemistry (still increasing)
Each product has passed very strict testing (NMR/MS/HPLC)
Agents from many countries

General tips：For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging：1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition：Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Details:

Chemical Properties of Kaempferol 3-O-arabinoside

Cas No.	99882-10-7
PubChem ID	5481882	Appearance	Yellow powder
Formula	C₂₀H₁₈O₁₀	M.Wt	418.4
Type of Compound	Flavonoids	Storage	Desiccate at -20°C
Solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name	5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxychromen-4-one
SMILES	C1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC=C(C=C4)O)O)O)O
Standard InChIKey	RNVUDWOQYYWXBJ-IEGSVRCHSA-N
Standard InChI	InChI=1S/C20H18O10/c21-9-3-1-8(2-4-9)18-19(30-20-17(27)15(25)12(24)7-28-20)16(26)14-11(23)5-10(22)6-13(14)29-18/h1-6,12,15,17,20-25,27H,7H2/t12-,15-,17+,20-/m0/s1
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging	1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment.
Shipping Condition	Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Kaempferol 3-O-arabinoside

The roots of Ligusticum jeholense Nakai et Kitag.

Biological Activity of Kaempferol 3-O-arabinoside

Description

Kaempferol-3-O-α-D-arabinoside displays cytotoxic and high antioxidant activity.Kaempferol-3-O-arabinoside and kaempferol-3-O-glucoside can function as antioxidants in biological systems, particularly skin exposed to UV radiation by scavenging ROS, and protect cellular membrane against ROS; they can be applicable to new cosmeceuticals for antioxidant, antiaging, and antibacterial activity.

Targets

Antifection | ROS

In vitro

Identification of the Major Polyphenols in Boysenberry Leaves and Their Suppressive Effect on Carbon Tetrachloride-Induced Liver Injury in Mice.[Reference: WebLink]

Food Science and Technology Research.2006 Feb;12(1):31-37.

Seven polyphenols were isolated from leaves of New Zealand boysenberry.
METHODS AND RESULTS:
On the basis of spectroscopic analysis, the structures of these compounds were elucidated to be quercetin 3-O-glucuronide, quercetin 3-O-glucoside, quercetin 3-O-arabinoside, kaempferol 3-O-glucuronide, Kaempferol 3-O-arabinoside, kaempferol 3-O-(6"-O-p-coumaroyl)-glucoside, and ellagic acid. Increases in plasma aspartate aminotrasferase and alanine aminotrasferase activities in mice, induced with liver injury by the injection of carbon tetrachloride, were suppressed by oral administration of the polyphenol fraction prepared from the leaves, with ellagic acid as its effective component.
CONCLUSIONS:
Thus polyphenol fraction contained in boysenberry leaves may be effective in suppressing liver injury.

Antibacterial, Antioxidative Activity and Component Analysis of Pinus koraiensis Leaf Extracts[Reference: WebLink]

Journal of the Society of Cosmetic Scientists of Korea.2010,36(4):303-14.

METHODS AND RESULTS:
In this study, the antibacterial, antioxidative effect and component analysis of Pinus koraiensis leaf extracts were investigated. MIC values of the ethyl acetate fraction from P. koraiensis leaf extracts on P. acnes, S. aureus, P. ovale, and E. coli were 0.06 %, 0.25 %, 0.13 % and 0.50 %, respectively. The results showed that the antibacterial activity of the ethyl acetate fraction on P. acnes, P. ovale. and S. aureus was more prominent. The aglycone fraction of P. koraiensis leaf extracts () showed more higher free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activity (). Reactive oxygen species (ROS) scavenging activity () of P. koraiensis leaf extracts on ROS generated in -EDTA/ system was investigated using the luminol-dependent chemiluminescence assay. The 50 % ethanol extract () showed the most prominent ROS scavenging activity. Also the ethyl acetate () and the aglycone fraction () showed very high antoxidant activity. The protective effects of extract/fractions of P. koraiensis leaf extracts on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. The P. koraiensis leaf extracts showed cellular membrane protective effects in a concentration dependent manner (). TLC and HPLC chromatogram of the ethyl acetate fraction obtained from hydrolysis of P. koraiensis leaf extracts revealed 2 main bands (PK-4, PK-6) and peaks (peak 1, peak 2), which were identified as kaempferol-3-O-glucoside (PK-6, peak 1) and Kaempferol 3-O-arabinoside (PK-4, peak 2) by LC/ESI-MS/MS, respectively.
CONCLUSIONS:
These results indicate that extract/fractions of P. koraiensis can function as antioxidants in biological systems, particularly skin exposed to UV radiation by scavenging ROS, and protect cellular membrane against ROS. Extract/fractions of P. koraiensis can be applicable to new cosmeceuticals for antioxidant, antiaging, and antibacterial activity.

Radical-Scavenging Activity, Cytotoxicity and Chemical Constituents of Euphorbia orthoclada from Madagascar.[Reference: WebLink]

Nat. Prod. J., 2013, 3: 77-80.

METHODS AND RESULTS:
Both cyclohexane and ethyl acetate fractions were toxic against brine shrimp larvae (Artemia salina) at a concentration of 10 μg/mL with mortality rates of 62% and 70%, respectively; however, the ethyl acetate extract proved to have the most effective antioxidant activity with an EC50 value of 3.45 ± 0.01 μg/mL. Five phenolic compounds 1-5 were isolated from the EtOAc extract by successive chromatographic procedures (silica gel, Sephadex LH-20). Among them, quercetin-3-O-α-D-arabinoside (2) (28.5 ± 0.11 μg/mL), kaempferol-3-O-β-D-glucoside (4) (37.2 ± 0.17 μg/mL), kaempferol-3-O-α-D-arabinoside (Kaempferol 3-O-arabinoside,3) (38.4 ± 0.13 μg/mL) and gallic acid (1) (55.22 ± 0.15 μg/mL) displayed the highest antioxidant activity, while 3,3',4'-trimethylellagic acid 4-O-glucoside (5) (63.90 ± 0.09 μg/mL) was more toxic than the other constituents on brine shrimp larvae when tested at 10 μg/mL (mortality rate of 65 %).
CONCLUSIONS:
The medicinal plant Euphorbia orthoclada - namely its chemical constituents - has been investigated for the first time in this project. The cytotoxic and antioxidant properties of the pure secondary metabolites explain the use of this plant in traditional medicine. Moreover, the isolation of compounds 2, 3 and 4 from E. orthoclada emphasizes that these metabolites may be considered as chemotaxonomic markers of the genus Euphorbia.

Preparing Stock Solutions of Kaempferol 3-O-arabinoside

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3901 mL	11.9503 mL	23.9006 mL	47.8011 mL	59.7514 mL
5 mM	0.478 mL	2.3901 mL	4.7801 mL	9.5602 mL	11.9503 mL
10 mM	0.239 mL	1.195 mL	2.3901 mL	4.7801 mL	5.9751 mL
50 mM	0.0478 mL	0.239 mL	0.478 mL	0.956 mL	1.195 mL
100 mM	0.0239 mL	0.1195 mL	0.239 mL	0.478 mL	0.5975 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Description

Kaempferol 3-O-arabinoside is an antioxidant flavonoids isolated from ethyl acetate fraction (EAF) obtained from the leaves of Nectandra hihua. Kaempferol 3-O-arabinoside has good antioxidant capacity.

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