- Min.Order :10 Milligram
- Purity: ≥98%
- Payment Terms : T/T
Keywords
Fraxinol 486-28-2 standard supplier in China
Quick Details
- Appearance:detailed see specifications
- Application:analysis,activity test,Botanical Reference Materials,Standard materials
- PackAge:According to the clients requirement.
- ProductionCapacity:1|Metric Ton|Day
- Storage:Store at 2~8°C
- Transportation:by air or by ocean shipping
Superiority:
Chemical Properties of Fraxinol
| Cas No. | 486-28-2 | ||
| PubChem ID | 3047739 | Appearance | White-yellowish powder |
| Formula | C11H10O5 | M.Wt | 222.2 |
| Type of Compound | Coumarins | Storage | Desiccate at -20°C |
| Synonyms | 6-Hydroxy 5,7-dimethoxycoumarin | ||
| Solubility | Soluble in DMSO and methanol; slightly soluble in water | ||
| Chemical Name | 6-hydroxy-5,7-dimethoxychromen-2-one | ||
| SMILES | COC1=C(C(=C2C=CC(=O)OC2=C1)OC)O | ||
| Standard InChIKey | PBPNOAHYDPHKFH-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C11H10O5/c1-14-8-5-7-6(3-4-9(12)16-7)11(15-2)10(8)13/h3-5,13H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Source of Fraxinol
The bark of Fraxinus chinensis Roxb
Biological Activity of Fraxinol
| Description | Fraxinol is a natural product from Lobelia chinensis. |
Protocol of Fraxinol
| Structure Identification |
Zhong Yao Cai. 2010 Nov;33(11):1721-4. Studies on the chemical constituents from Lobelia chinensis.[Pubmed: 21434431] To study the chemical constituents of the full plant of Lobelia chinensis. |
Preparing Stock Solutions of Fraxinol
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.5005 mL | 22.5023 mL | 45.0045 mL | 90.009 mL | 112.5113 mL |
| 5 mM | 0.9001 mL | 4.5005 mL | 9.0009 mL | 18.0018 mL | 22.5023 mL |
| 10 mM | 0.45 mL | 2.2502 mL | 4.5005 mL | 9.0009 mL | 11.2511 mL |
| 50 mM | 0.09 mL | 0.45 mL | 0.9001 mL | 1.8002 mL | 2.2502 mL |
| 100 mM | 0.045 mL | 0.225 mL | 0.45 mL | 0.9001 mL | 1.1251 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
References on Fraxinol
New constituents of Artemisia monosperma Del.[Pubmed:18771012]
Pharmazie. 2008 Aug;63(8):611-4.
Phytochemical investigation of air-dried powdered roots of Artemisia monosperma growing in Egypt afforded two new compounds; 6-hydroxy-7,8-dimethoxycoumarin (I) and 5-acetyl-2-[1'-(hydroxymethyl)ethyl]-2,3-dihydrobenzo[b]furan (IV), in addition to the known compounds; 6-hydroxy-5,7-dimethoxycoumarin (Fraxinol) (II), 5-hydroxy-6,7-dimethoxycoumarin (tomentin) (III) and methyl-beta-D-fructofuranoside (V), obtained for the first time from the plant. Chemical structures of the isolated compounds were assigned based on different physical, chemical and spectroscopic techniques including UV, IR, MS, 1D- and 2D-NMR spectra. Furthermore, antimicrobial activity of different extracts of roots was carried out.
[Studies on the chemical constituents from Lobelia chinensis].[Pubmed:21434431]
Zhong Yao Cai. 2010 Nov;33(11):1721-4.
OBJECTIVE: To study the chemical constituents of the full plant of Lobelia chinensis. METHODS: The compounds were isolated and purified using several column chromatographic methods. Their structures were elucidated based on their physicochemical properties and spectral data. RESULTS: Twelve compounds were isolated from L. chinensis. Their structures were elucidated as 6,7-dimethoxycoumarin (1), Fraxinol (2), 5-hydroxy-7-methoxycoumarin (3), tomentin (4), 3'-hydroxygenkwanin (5), apigenin (6), quercetin (7), luteolin (8), linarin (9), luteolin 3',4'-dimethylether-7-O-beta-D-glucoside (10), isoferulic acid (11), and ethyl ros-marinate (12), respectively. CONCLUSION: Compounds 1 -5 and 10 -12 are isolated from this plant for the first time.
Description
Fraxinol is isolated from Lobelia chinensis.
Keywords:
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Details:
Quantity:1mg-1kg
Function:analysis,activity test,Botanical Reference Materials,Standard materials
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