Aloperine 56293-29-9 standard supplier in China
Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine), Natural Active Pharmaceutical Ingredients worldwide. From small quantities for R&D or reference standard, to large quantities for customizing or manufacturing, Biopurify emphasizes on consistent and reliable services for his customers.
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We are doing our best to be your reliable partner for high quality Phytochemicals and Reference Standards from china.
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General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging:1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition:Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.
Cas No. | 56293-29-9 | SDF | |
PubChem ID | 162147 | Appearance | Colorless prismatic crystal |
Formula | C15H24N2 | M.Wt | 232.36 |
Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
Solubility | >9.25mg/mL in DMSO | ||
Chemical Name | (1R,2S,9R,10R)-3,15-diazatetracyclo[7.7.1.02,7.010,15]heptadec-7-ene | ||
SMILES | C1CCN2CC3CC(C2C1)C=C4C3NCCC4 | ||
Standard InChIKey | SKOLRLSBMUGVOY-GBJTYRQASA-N | ||
Standard InChI | InChI=1S/C15H24N2/c1-2-7-17-10-13-9-12(14(17)5-1)8-11-4-3-6-16-15(11)13/h8,12-16H,1-7,9-10H2/t12-,13+,14+,15+/m0/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
The herbs of Sophora alopecuroides L.
Description | 1. Aloperine has antitumor effects , it can suppress the tumor growth and promote cell apoptosis and cell cycle arrest in PCa cells. 2. Aloperine protects mice against bleomycin-induced pulmonary fibrosis by attenuating fibroblast proliferation and differentiation. 3. Aloperine exhibits neuroprotective effects against oxidative stress in vitro, it can ameliorate oxidative damage against early brain injury following subarachnoid hemorrhage , most likely via the Nrf2-ARE survival pathway. 4. Aloperine attenuates hydrogen peroxide-induced injury via anti-apoptotic activity and suppression of the nuclear factor-κB signaling pathway. 5. Aloperine exerts significant inhibitive effects on acute inflammation and Type III and IV hypersensitivity caused by a variety of inflammatory agents. |
Targets | c-Myc | Caspase | ERK | p21 | Bcl-2/Bax | p53 | PI3K | mTOR | TNF-α | Akt | TGF-β/Smad | Nrf2 | HO-1 | NF-kB |
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 4.3037 mL | 21.5183 mL | 43.0367 mL | 86.0733 mL | 107.5917 mL |
5 mM | 0.8607 mL | 4.3037 mL | 8.6073 mL | 17.2147 mL | 21.5183 mL |
10 mM | 0.4304 mL | 2.1518 mL | 4.3037 mL | 8.6073 mL | 10.7592 mL |
50 mM | 0.0861 mL | 0.4304 mL | 0.8607 mL | 1.7215 mL | 2.1518 mL |
100 mM | 0.043 mL | 0.2152 mL | 0.4304 mL | 0.8607 mL | 1.0759 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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